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Picture of David Besselsen

David Besselsen

Adjunct Associate Professor, Animal and Comparative Biomedical Sciences | Veterinary Specialist | Member of the Graduate Faculty | Associate Research Scientist, BIO5 Institute

RII Research Infrastructure

Collaboration(48)

Cynthia Thomson
Denise Roe
Janko Nikolich
Sharon Dial
Russell Witte

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Grants(6)

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Publications(95)

Recent

Decreased NHE3 expression in colon cancer is associated with DNA damage, increased inflammation and tumor growth

2022

colon cancer, dna damage, inflammation, tumor growth, gene expression

Kallikrein 6 enzyme deficiency in the colon attenuates the Apc-mutant colon carcinogenesis

2022

enzyme deficiency, colon carcinogenesis, apc-mutant, kallikrein 6, colon

Infection-induced type I interferons critically modulate the homeostasis and function of CD8+ naïve T cells.

2021

infections, immune response, t cell function, interferons, homeostasis

Novel Mouse Models of Fungal Asthma

2021

mouse models, fungal asthma, novel models, fungal infections, respiratory diseases

Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice.

2020

intestinal epithelial, mhcii, colitis, t-cell-induced, infectious

Total CD3 T Cells Are Necessary and Sufficient to Induce Colitis in Immunodeficient Mice With Dendritic Cell-Specific Deletion of TGFbR2: A Novel IBD Model to Study CD4 and CD8 T-Cell Interaction.

2020

inflammatory bowel disease, immunology, t-cell interaction, dendritic cells, mouse model

Preclinical evidence in support of repurposing sub-anesthetic ketamine as a treatment for L-DOPA-induced dyskinesia.

2020

ketamine, l-dopa-induced dyskinesia, preclinical evidence, treatment, repurposing

Sexual Dimorphism in the Response to Broad-spectrum Antibiotics During T Cell-mediated Colitis.

2019

sexual dimorphism, antibiotics, t cell-mediated colitis, response, broad-spectrum

Silicon Foreign Body in the Cerebrum of a Rhesus Macaque.

2019

neuroscience, biomedical engineering, animal research, surgery, materials science

Does Mutated K-RAS Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?

2018

k-ras, colon cancer, chemoprevention, mutated gene, sulindac