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Russell S. Witte graduated with Honors in Physics (BS, 1993) from University of Arizona and Bioengineering (PhD, 2002) from Arizona State University, where he used electrode arrays to study sensory coding and learning-induced plasticity in the brain. As a postdoctoral fellow at the University of Michigan, he helped devise state-of-the-art techniques to image the nervous and musculoskeletal systems. Dr. Witte is now Associate Professor of Medical Imaging, Biomedical Engineering, and Optical Sciences at the University of Arizona. His Experimental Ultrasound and Neural Imaging Laboratory (EUNIL) devises hybrid imaging methods that integrate light, ultrasound, and microwaves for advanced imaging with novel contrast. These noninvasive techniques, such as acoustoelectric imaging, thermoacoustic imaging, and ultrasound elastography, quantify changes in the electrical, optical and/or mechanical properties of tissue at high spatial resolution. The ultimate goal of Dr. Witte’s research is to improve patient care by providing tools that improve diagnostic accuracy and treatment-decision making for a variety of conditions ranging from epilepsy and arrhythmia to tendinopathy and cancer.Show Less
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Courses
- AMIAdvanced Medical Imaging
- CAMIKContrast Agents, Molecular Imaging, and Kinetics
Grants
- High School Student NeuroResearch Program (HSNRP)
Multiple Principal Investigator (MPI)
2023
$134.9K
Active - 4D Transcranial Acoustoelectric Imaging for High Resolution Functional Mapping of Neuronal Currents
Principal Investigator (PI)
2020
$2.1M
Active - Acoustoelectric Echocardiography for Improving Prognosis and Guiding Treatment Decisions for Advanced Arrhythmias
Principal Investigator (PI)
2020
$99.8K
Active - Bioengineered Skin Sealants
Principal Investigator (PI)
2020
$85.1K
Active - High School Student NeuroResearch Program (HSNRP)
Multiple Principal Investigator (MPI)
2016
$561.6K
Active - 4D Transcranial Acoustoelectric Imaging for High Resolution Functional Mapping of Neuronal Currents
Principal Investigator (PI)
2019
$428.3K
- Acoustoelectric Imaging
Principal Investigator (PI)
2019
$460.5
- 4D Acoustoelectric Cardiac Imaging for Fast and Accurate Mapping of Arrhythmias
Principal Investigator (PI)
2018
$73.8K
- Integrated Platform for Spectroscopic Thermoacoustic Imaging and Focused Microwave Therapy of the Breast
Principal Investigator (PI)
2016
$741.3K
- Ultrasound Elasticity Imaging (UEI)
Principal Investigator (PI)
2016
$378.0
News
- UArizona Reports Record Number of Startups for Fiscal Year 2020
2020
- Startup Sees Future for Heart Imaging Technology
2019
- UA Researchers Develop Brain-Mapping Technology
2015
- BIO5 Institute Funds Eight Collaborative Pilot Grants
2012
- Fighting Disease With Lasers, Light
2010
- Better Than Ever Helps Employees Get Fit and Fight Cancer
2010
- Memorial Service for Dr. Charles Witte March 20
2003
Publications (115)
Recent
- Current Source Density Imaging Using Regularized Inversion of Acoustoelectric Signals
2022
- Transparent Gellan Gum as an Efficient Coupling Media For Photoacoustic Imaging Applications
2022
- Temporal evaluation of efficacy and quality of tissue repair upon laser‐activated sealing
2022
- Hyperacute pathophysiology of traumatic and vascular brain injury captured by ultrasound, photoacoustic, and magnetic resonance imaging
2021
- 4D Reconstruction and Identification of Carotid Artery Stenosis Utilizing a Novel Pulsatile Ultrasound Phantom
2021
- Real-Time Trimodal Ultrasound, Photoacoustic, and Thermoacoustic Imaging for Biomedical Applications
2021
- Lymphatic system and cancer metastasis
2020
- Activation of hippocampal CA2 precedes CA3 following perforant-path stimulation and spontaneous dentate spikes.
2020
- Tracking Tumor Growth and Angiogenesis in Mouse Models of Breast Cancer with Perfluorocarbon Microbubbles
2018
- Tracking delivery of a drug surrogate in the porcine heart using photoacoustic imaging and spectroscopy
2017
- Abstract 86: Mapping and Inducing Ventricular Tachycardia in Cardiomyopathic Animal Models
2017
- A model for use in the prognosis of tendinopathy
2017
- Microwave-Induced Thermoacoustic Communications
2017
- 4D Acoustoelectric Imaging of Current Sources in a Human Head Phantom
2016
- IN VIVO ULTRASOUND ELASTICITY IMAGING CLASSIFIES HEALTHY AND DISEASED POSTERIOR TIBIAL TENDONS
2016
- Abstract 71: Model of Induced Ventricular Tachycardia and Cardiac Electrophysiological Mapping
2016
- Intracellular delivery and ultrasonic activation of folate receptor-targeted phase-change contrast agents in breast cancer cells in vitro
2016
- Model of Induced Ventricular Tachycardia and Cardiac Electrophysiological Mapping
2016
- Minimizing strain error for in vivo ultra-sound elasticity imaging of human tendon
2016
- Thermoacoustic and photoacoustic characterizations of few-layer graphene by pulsed excitations
2016
- Complementary Detection of Multiple Electrical Sources in Tissue Using Acoustoelectric Effects
2016
- Advances in Lower Extremity Ultrasound
2015
- Broadband Spectroscopic Thermoacoustic Characterization of Single-Walled Carbon Nanotubes
2015
- Experimental Validation of a Numerical Model for Thermoacoustic Imaging Applications
2015
- Fabrication of a realistic breast phantom based on 3D printing technology for thermoacoustic imaging application in breast cancer detection
2015
- Impact of Microwave Pulses on Microwave-Induced Thermoacoustic Imaging Applications
2015
- A pilot study of ultrasound-guided electronic brachytheropy for skin cancer
2015
- Ultrasound Current Source Density Imaging of the Cardiac Activation Wave Using a Clinical Cardiac Catheter
2015
- Computational Feasibility Study of Contrast-Enhanced Thermoacoustic Imaging for Breast Cancer Detection Using Realistic Numerical Breast Phantoms
2015
- Thermoacoustic Applications in Breast Cancer Imaging, Non-contact Explosive Detection and Communications
2015
- Compressive Sensing Based Contrast-Enhanced Thermoacoustic Imaging for Breast Cancer Detection
2015
- Tracking Mass Transport of a Drug Surrogate in Porcine Coronary Tissue using Photoacoustic Imaging and Spectroscopy
2015
- Modeling of non-contact thermoacoustic imaging
2015
- RETENTION AND TRANSPORT OF HYDROPHOBIC AND HYDROPHILIC DRUG SURROGATE MOLECULES IN CORONARY ARTERIES MEASURED NONDESTRUCTIVELY WITH PHOTOACOUSTIC ULTRASOUND
2014
- Non-contact thermoacoustic imaging based on laser and microwave vibrometry
2014
- Performance Improvement for Thermoacoustic Imaging Using Compressive Sensing
2014
- Thermoacoustic Imaging and Spectroscopy for Enhanced Breast Cancer Detection
2014
- Artifacts in musculoskeletal ultrasonography
2014
- Inexpensive acoustoelectric hydrophone for measuring high intensity ultrasound fields
2014
- Computational Study of Thermoacoustic Imaging for Breast Cancer Detection Using a Realistic Breast Model
2014
- A novel optical imaging system for investigating sarcomere dynamics in single skeletal muscle fibers - art. no. 608808
2014
- An electrically coupled tissue-engineered cardiomyocyte scaffold improves cardiac function in rats with chronic heart failure
2014
- Simulation-based validation for four- dimensional multi-channel ultrasound current source density imaging
2014
- Error analysis of axial displacement estimation in elasticity imaging
2014
- In vivo multi-modality photoacoustic and pulse echo tracking of prostate tumor growth using a window chamber
2013
- Implantation of an Electrically Coupled Cardiomyocyte Scaffold Improves Left Ventricular Ejection Fraction in Rats 18 Weeks after Implantation
2013
- Microwave Induced Thermal Acoustic Imaging Modeling for Potential Breast Cancer Detection
2013
- Measurement of a 2D electric dipole field using the acousto-electric effect - art. no. 65130S
2013
- Hybrid imaging system for developing novel neural contrast agents
2013
- Simulation-Based Validation for Four-Dimensional Multi-Channel Ultrasound Current Source Density Imaging
2013
- Simultaneous Detection of Multiple Contrast Agents with Photoacoustic Spectroscopy
2012
- Broadband Thermoacoustic Spectroscopy of Single Walled Carbon Nanotubes
2012
- Fabrication and characterization of an indium tin oxide acoustoelectric hydrophone
2012
- Impact of Microwave Pulses on Thermoacoustic Imaging Applications
2012
- Ultrasound Imaging of the Mouse Pancreatic Duct using Lipid Microbubbles.
2012
- Cardiac activation mapping with ultrasound current source density imaging
2012
- Mapping the ECG in the live rabbit heart using Ultrasound Current Source Density Imaging with coded excitation
2012
- A Hybrid Microwave/Acoustic Communication Scheme - Thermoacoustic Communication
2012
- Optimizing Frequency and Pulse Shape for Ultrasound Current Source Density Imaging
2012
- Ultrasound Current Source Density Imaging Using a Clinical Intracardiac Catheter
2012
- Electric current mapping using the acousto-electric effect - art. no. 61470O
2011
- Diagnostic and therapeutic imaging for cancer: therapeutic considerations and future directions
2011
- Microwave-Induced Thermoacoustic Imaging Model for Potential Breast Cancer Detection
2011
- Time-Efficient Contrast-Enhanced Thermoacoustic Imaging Modality for 3-D Breast Cancer Detection Using Compressive Sensing
2011
- Four-dimensional ultrasound current source density imaging of a dipole field
2011
- 3-D photoacoustic and pulse echo imaging of prostate tumor progression in the mouse window chamber
2011
- Measuring the acoustoelectric interaction constant using ultrasound current source density imaging
2010
- Comparisons of Planar and Tubular Biaxial Tensile Testing Protocols of the Same Porcine Coronary Arteries
2010
- Tracking contrast agents using real-time 2D photoacoustic imaging system for cardiac applications
2010
- Simulation-Based Optimization of the Acoustoelectric Hydrophone for Mapping an Ultrasound Beam
2010
- Real-time photoacoustic and ultrasound imaging: a simple solution for clinical ultrasound systems with linear arrays
2010
- Design Considerations and Performance of MEMS Acoustoelectric Ultrasound Detectors
2010
- Contrast-enhanced photoacoustic imaging of live lobster nerve cord - art. no. 64370J
2009
- Imaging current flow in lobster nerve cord using the acoustoelectric effect
2009
- Cardiac activation mapping using ultrasound current source density imaging (UCSDI)
2009
- Two-dimensional strain imaging of controlled rabbit hearts
2009
- Spectroscopic thermoacoustic imaging of water and fat composition
2009
- Arterial vulnerable plaque characterization using ultrasound-induced thermal strain imaging (TSI)
2008
- Mapping Cardiac Currents using Ultrasound Current Source Density Imaging
2008
- Analysis of correlation coefficient filtering in elasticity imaging
2008
- Real-Time Pulse Echo and Photoacoustic Imaging Using an Ultrasound Array and In-line Reflective Illumination
2008
- Thin polymer etalon arrays for high-resolution photoacoustic imaging
2008
- Detection of Multiple Electrical Sources in Tissue Using Ultrasound Current Source Density Imaging
2008
- Ultrasound current source density imaging
2008
- In vivo imaging of inflammatory responses by photoacoustics using cell-targeted gold nanorods (GNR) as contrast agent - art. no. 68560H
2008
- Inducing and imaging thermal strain using a single ultrasound linear array
2007
- Fast wave propagation in auditory cortex of an awake cat using a chronic microelectrode array
2007
- Ultrasound Elasticity Imaging for Determining the Mechanical Properties of Human Posterior Tibial Tendon: A Cadaveric Study
2007
- Enhanced photoacoustic neuroimaging with gold nanorods and PEBBLEs - art. no. 685614
2007
- Fast wave propagation in auditory cortex of an awake cat using a chronic microelectrode arrayThe work was performed at Department of Bioengineering, Arizona State University, ECG 334 MS-9709 Arizona State University, Tempe, AZ 85287-9709, USA.
2007
- Controlled 2D cardiac elasticity imaging on an isolated perfused rabbit heart
2007
- Inexpensive acoustoelectric hydrophone for mapping high intensity ultrasonic fields
2007
- Microwave-Induced Thermoacoustic Imaging for Embedded Explosives Detection
2007
- Motion artifact reduction by ECG gating in ultrasound induced thermal strain imaging
2007
- 8F-6 Inexpensive Acoustoelectric Hydrophone For Measuring High Intensity Ultrasound Fields
2007
- Detection of electrical current in a live rabbit heart using ultrasound
2007
- Toward fiber-based high-frequency 3D ultrasound imaging - art. no. 643728
2007
- Ultrasound elasticity Imaging of muscle fatigue in the human forearm: Implications for muscle injury and recovery
2006
- IVUS beyond the horizon
2006
- Acoustoelectric Detection of Current Flow in a Neural Recording Chamber
2006
- Feasibility of Inducing and Imaging Thermal Strain for High-risk Plaque Identification in Peripheral Arteries Using Ultrasound Arrays
2006
- Quality Improvement of Thermoacoustic Imaging Based on Compressive Sensing
2006
- Effect of fatigue on muscle elasticity in the human forearm using ultrasound strain imaging
2006
- High frequency ultrasound imaging using Fabry-Perot optical etalon
2005
- Tissue microscopy using optical generation and detection of ultrasound
2005
- Real-time, contrast enhanced photoacoustic imaging of cancer in a mouse window chamber
2005
- Enhanced contrast sensitivity in auditory cortex as cats learn to discriminate sound frequencies
2005
- Identification of vulnerable atherosclerotic plaque using IVUS-based thermal strain imaging
2005
- Application of ultrasonic thermal imaging in IVUS systems
2004
- High resolution ultrasound imaging of skeletal muscle dynamics and effects of fatigue
2004
- Microwave-induced thermal imaging of tissue dielectric properties
2003
- Ultrasonic thermal imaging of microwave absorption
2003
- Pursuing dynamic reorganization in auditory cortex using chronic, multichannel unit recordings in awake, behaving cats
1999
- Functional connectivity in auditory cortex using chronic, multichannel unit recordings
1999