Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce pain, inflammation, and swelling in conditions such as arthritis. Research on sulindac primarily focuses on its anti-inflammatory and pain-relieving properties, as well as its potential side effects and long-term use. Studies have also investigated the efficacy of sulindac in treating various types of cancer, including colorectal cancer. Overall, research in this area aims to better understand the mechanisms of action of sulindac and optimize its use for various medical conditions.