The University of Arizona
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Vadim Pivniouk

Assistant Research Scientist, Respiratory Sciences | Associate Research Professor, Cellular and Molecular Medicine - (Research Series Track)

College of Medicine - Tucson
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20+ Collaborators
$2.6M / $34.4M Funding
6+ Grants
20+ Publications

Research Area

asthma, immunology, allergy, respiratory health, immune response, disease susceptibility, genetics, gene regulation, gene expression, innate immunity

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    Recent

    Immune modulation by rural exposures and allergy protection

    2024
    immune modulation, rural exposures, allergy protection

    Administration of a Bacterial Lysate to the Airway Compartment Is Sufficient to Inhibit Allergen-Induced Lung Eosinophilia in Germ-free Mice

    2023
    immunology, microbiology, respiratory health, animal studies, allergy

    Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis

    2021
    asthma, dendritic cells, epithelium, il-33, ilc2

    The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression

    2021
    bacterial lysate, sars-cov-2 infection, epithelial cells, downregulating receptor expression, immune response modulation

    The role of innate immunity in asthma development and protection: Lessons from the environment.

    2020

    Gut microbiota from Amish but not Hutterite pre-school children protect germ-free mice from experimental asthma

    2018
    microbiota, children, asthma, mice, amish

    Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

    2016
    innate immunity, asthma risk, amish, hutterite, farm children

    Downregulation of human IL4 and IL13 expression by CRISPR/Cas9-mediated deletion of DNase I hypersensitive site HS11/12 from a transgenic human Th2 cytokine locus

    2016
    crispr/cas9, gene expression, immunology, genetic engineering, biotechnology

    Differential regulation of human and mouse IL33 expression in the lungs of human IL33 BAC transgenic mice.

    2016
    gene expression, immunology, transgenic mice, respiratory system, regulation

    Asthma/allergy-associated single nucleotide polymorphisms SNPs) in IL13 strongly dysregulate human IL4 expression and IgE production

    2013
    genetics, immunology, asthma, allergy, gene regulation

    • Fernando Martinez

    • Janko Nikolich

    • Tara Carr

    • Dean Billheimer

    • Lynn Gerald

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    • Vercelli Laboratory

      The Vercelli laboratory at the University of Arizona investigates the impact of environmental, genetic and developmental factors on the pathogenesis of allergic diseases, focusing on the mechanisms underlying protection from asthma and allergies. Work in animal and human models shows that microbial products from traditional dairy farms and lysates of airway bacteria confer strong protection through innate immune mechanisms.

    • Cell Biology of Disease

    Vadim Pivniouk | KMap Profile - Institutional Knowledge Map (KMap)