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Pawel Kiela

Member of the Graduate Faculty | Associate Professor, Physiological Sciences - GIDP | Research Professor, Immunobiology | Professor, Pediatrics

Pediatrics
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50+ Collaborators
$9.1M / $29.9M Funding
20+ Grants
160+ Publications
6+ Tech/Patents
10+ News

Research Area

inflammation, colitis, microbiome, inflammatory bowel disease, dendritic cells, immunology, immune response, intestinal health, mouse model, gut microbiota, gene expression, microbiota, gut microbiome, curcumin, inflammatory bowel diseases, modulation, pathogenesis, ion channels, gastroenterology, experimental colitis, intestinal barrier, dynamics, colorectal cancer, gastrointestinal physiology, cellular transport, nutrition, antibiotics, parylation, intestinal transport

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    Recent

    NHE3 Controls Proliferation and Migration of Colonic Epithelial Cells

    2025

    Oral Delivery of miR146a Conjugated to Cerium Oxide Nanoparticles Improves an Established T Cell-Mediated Experimental Colitis in Mice

    2024
    nanoparticle delivery, oral delivery

    The Na/Ca exchanger NCX3 mediates Ca entry into matrix vesicles to facilitate initial steps of mineralization in osteoblasts

    2024

    Intestinal lysozyme engagement of Salmonella Typhimurium stimulates the release of barrier-impairing InvE and Lpp1

    2024
    salmonella infection, host-pathogen interaction, immune response

    Transplant of microbiota from Crohn's disease patients to germ-free mice results in colitis

    2024
    microbiota, crohn's disease, transplant, colitis

    The arginine and nitric oxide metabolic pathway regulate the gut colonization and expansion of Ruminococcous gnavus

    2024
    microbiome, metabolism, nitric oxide, pathogenesis, immune response

    Infection and inflammation stimulate expansion of a CD74 Paneth cell subset to regulate disease progression

    2023
    infection, inflammation, cd74, paneth cell, disease progression

    Gut microbiota modulates PARP1-driven PARylation to control colonic inflammation

    2022
    microbiota, inflammation, parylation, colonic, modulation

    Interactions between arsenic exposure, high-fat diet and NRF2 shape the complex responses in the murine gut microbiome and hepatic metabolism

    2022
    arsenic exposure, high-fat diet, nrf2, gut microbiome, hepatic metabolism

    Decreased NHE3 expression in colon cancer is associated with DNA damage, increased inflammation and tumor growth

    2022
    colon cancer, dna damage, inflammation, tumor growth, gene expression

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    • Introduction to Microbiome Community Analysis Methods

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    Pawel Kiela | KMap Profile - Institutional Knowledge Map (KMap)