ACE2, or angiotensin converting enzyme 2, is an enzyme that plays a crucial role in the Renin-Angiotensin System, which regulates blood pressure and fluid balance in the body. ACE2 is known for its role in infectious diseases, particularly as the receptor that the SARS-CoV-2 virus uses to enter and infect cells, leading to the COVID-19 pandemic. Research in the ACE2 field focuses on understanding its function in health and disease, developing treatments that target ACE2, and exploring its potential as a therapeutic target for various conditions. Studies also investigate the interactions between ACE2 and other molecules in the body, as well as its role in different organ systems.