KMap
Jeong-Yeol Yoon received his B.S., M.S. and Ph.D. degrees in Chemical Engineering from Yonsei University, Seoul (South Korea) in 1992, 1994 and 1999, respectively, under the guidance of Professor Woo-Sik Kim, in collaboration with Professor Jung-Hyun Kim, where he worked primarily on polymer colloids. He received his second Ph.D. degree in Biomedical Engineering from University of California, Los Angeles in 2004, working on lab-on-a-chip and biomaterials, under the guidance of Professor Robin L. Garrell. He joined Department of Agricultural & Biosystems Engineering faculty in August 2004 and holds joint appointment in School of Animal & Comparative Biomedical Sciences, Department of Biomedical Engineering and BIO5 Institute at The University of Arizona. He is currently directing Biosensors Lab. Dr. Yoon is a member of IBE, ASABE and SPIE, and was Councilor-at-Large for IBE for 2010 and 2011 calendar years. He has recently been elected as President of IBE, and will serve as President Elect in 2014, President in 2015, and Immediate Past President in 2016. He currently serves as Editor-in-Chief for Journal of Biological Engineering (IBE), Associate Editor for ASABE Journals; Editorial Board Member for Resource Magazine (ASABE).

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Courses
  • SC
    Sensors and Controls

  • BTI
    Biomaterial-Tissue Interactions

  • CTE
    Cell and Tissue Engineering

Grants
  • Funding agency logo
    Portable Micro- and Nanoplastics Detection

    Principal Investigator (PI)

    2023

    $76.3K
    Active
  • Funding agency logo
    Smartphone- and Paper Microfluidic-Based Detection of eNAMPT from Blood

    Principal Investigator (PI)

    2022

    $85.6K
    Active
  • Funding agency logo
    Adapting Oil Fingerprinting Analysis with Smartphone Agency

    Principal Investigator (PI)

    2018

    $261.1K
  • Funding agency logo
    Assaying Zika Virus through Monitoring Interfacial Effects on Paper/Phase 2 (WAESO)

    Principal Investigator (PI)

    2017

    $376.6
  • Funding agency logo
    Cardiovascular Biomedical Engineering Training Grant

    Co-Investigator (COI)

    2016

    $1.9M
  • Funding agency logo
    Assaying Zika Virus through Monitoring Interfacial Effects on Paper (WAESO)

    Principal Investigator (PI)

    2016

    $378.0
  • Funding agency logo
    RAPID: Development of a Handheld, Rapid Molecular Diagnostic Tool for Ebola

    Co-Investigator (COI)

    2015

    $211.2K
  • Funding agency logo
    Direct Identification/Quantification of Particulate Matter from Air Purifier

    Principal Investigator (PI)

    2014

    $289.6K
  • Funding agency logo
    Paper Microfluidics from Urinalysis

    Principal Investigator (PI)

    2014

    $286.0K
  • Funding agency logo
    Handheld, Wire-Guided Droplet PCR Device for Veterinary Diagnostics

    Principal Investigator (PI)

    2012

    $138.0K
Technologies / Patents
      Books
      • Introduction to Biosensors: From Electric Circuits to Immunosensors

        2013

      News
      • UArizona Researchers Develop Smartphone-Based COVID-19 Test

        2021

      • Using a Smartphone to Detect Norovirus

        2019

      • Device Could Speed Diagnosis of Infections

        2015

      • UA Ag and Cardiology Profs Team Up to Make Implanted Devices 'Sticky'

        2013

      • Two UA Inventions Selected as AZ Furnace Startups

        2012

      • BIO5 Institute Funds Eight Collaborative Pilot Grants

        2012

      • ‘Lab on a Chip’ Detects Human, Agricultural Contaminants

        2010

      • Grants & Awards March 2005 Total $553,591

        2005

      Publications (149)
      Recent
      • Capillary flow velocity profile analysis on paper-based microfluidic chips for screening oil types using machine learning

        2023

      • Rapid, sensitive detection of PFOA with smartphone-based flow rate analysis utilizing competitive molecular interactions during capillary action

        2023

      • Microfluidic detection of viruses for human health

        2022

      • Machine learning classification of bacterial species using mix-and-match reagents on paper microfluidic chips and smartphone-based capillary flow analysis

        2022

      • Flow rate profile based PFAS detection on smartphone- and paper-based microfluidics

        2022

      • Machine Learning-Based Quantification of (−)-trans-Δ-Tetrahydrocannabinol from Human Saliva Samples on a Smartphone-Based Paper Microfluidic Platform

        2022

      • Smartphone-based sensitive detection of SARS-CoV-2 from saline gargle samples via flow profile analysis on a paper microfluidic chip

        2022

      • Direct Capture and Smartphone Quantification of Airborne SARS-CoV-2 on a Paper Microfluidic Chip

        2022

      • Smartphone-based autofluorescence imaging to detect bacterial species on laboratory surfaces

        2022

      • Biosensor Detection of Airborne Respiratory Viruses Such As SARS-CoV-2

        2022

      • Bioanalytical approaches for the detection, characterization, and risk assessment of micro/nanoplastics in agriculture and food systems

        2022

      • Smartphone-based paper microfluidic competitive immunoassay for the detection of α-amanitin from mushrooms

        2022

      • Natural Killer Cell Detection, Quantification, and Subpopulation Identification on Paper Microfluidic Cell Chromatography Using Smartphone-based Machine Learning Classification

        2022

      • COVID-19 variants’ cross-reactivity on the paper microfluidic particle counting immunoassay

        2022

      • Machine learning techniques for chemical and type analysis of ocean oil samples via handheld spectrophotometer device

        2022

      • Microscopic Imaging Methods for Organ-on-a-Chip Platforms

        2022

      • Sensitive, smartphone-based SARS-CoV-2 detection from clinical saline gargle samples

        2022

      • Progression of LAMP as a Result of the COVID-19 Pandemic: Is PCR Finally Rivaled?

        2022

      • A guanidinium-rich polymer as a new universal bioreceptor for multiplex detection of bacteria from environmental samples

        2021

      • Machine Learning Enhances the Performance of Bioreceptor-Free Biosensors

        2021

      • Emulsion-based Isothermal Nucleic Acid Amplification for Rapid SARS-CoV-2 Detection via Angle-dependent Light Scatter Analysis

        2021

      • Microfluidic Sample Preparation for Respiratory Virus Detection: A Review

        2021

      • Human Sensor-inspired Supervised Machine Learning of Smartphone-based Paper Microfluidic Analysis for Bacterial Species Classification

        2021

      • Contamination-resistant, Rapid Emulsion-based Isothermal Nucleic Acid Amplification with Mie-scatter Inspired Light Scatter Analysis for Bacterial Identification

        2021

      • Environmental Toxicology Assays Using Organ-on-Chip

        2021

      • FEAST of Biosensors: Food, Environmental and Agricultural Sensing Technologies (FEAST) in North America

        2021

      • In situ sensors for blood-brain barrier (BBB) on a chip

        2021

      • Norovirus Detection in Water Samples at the Level of Single Virus Copies per Microliter Using a Smartphone-based Fluorescence Microscope

        2021

      • Proximal Methods for Plant Stress Detection Using Optical Sensors and Machine Learning

        2020

      • Handheld UV Fluorescence Spectrophotometer Device for the Classification and Analysis of Petroleum Oil Samples

        2020

      • The Future of Microbiome Analysis: Biosensor Methods for Big Data Collection and Clinical Diagnostics

        2020

      • Smartphone based on-chip fluorescence imaging and capillary flow velocity measurement for detecting ROR1+ cancer cells from buffy coat blood samples on dual-layer paper microfluidic chip

        2020

      • Label-free Mie Scattering Identification of Tumor Tissue Using an Angular Photodiode Array

        2020

      • Paper-based In Vitro Tissue Chip for Delivering Programmed Mechanical Stimuli of Local Compression and Shear Flow

        2020

      • Simple Paper-based Liver Cell Model for Drug Screening

        2020

      • Chromogenic Polymers and Their Packaging Applications: A Review

        2020

      • Interfacial Effect-Based Quantification of Droplet Isothermal Nucleic Acid Amplification for Bacterial Infection

        2019

      • Methods of Delivering Mechanical Stimuli to Organ-on-a-Chip

        2019

      • Simplified White Blood Cell Differential: An Inexpensive, Smartphone- and Paper-Based Blood Cell Count

        2019

      • Microfluidic Point-of-care Ecarin Based Clotting and Chromogenic Assays for Monitoring Direct Thrombin Inhibitors

        2019

      • Distance versus Capillary Flow Dynamics‐Based Detection Methods on a Microfluidic Paper‐Based Analytical Device (μPAD)

        2019

      • Colorimetric Array Freshness Indicator and Digital Color Processing for Monitoring the Freshness of Packaged Chicken Breast

        2019

      • Mie Scattering and Microparticle-Based Characterization of Heavy Metal Ions and Classification by Statistical Inference Methods

        2019

      • Flow Rate and Raspberry Pi-based Paper Microfluidic Blood Coagulation Assay Device

        2019

      • Smartphone-Based Paper Microfluidic Particulometry of Norovirus from Environmental Water Samples at the Single Copy Level

        2019

      • Challenges in Paper-Based Fluorogenic Optical Sensing with Smartphones

        2018

      • Smartphone Near Infrared Monitoring of Plant Stress

        2018

      • A Capillary Flow Dynamics-Based Sensing Modality for Direct Environmental Pathogen Monitoring

        2018

      • Simpler, Faster, and Sensitive Zika Virus Assay Using Smartphone Detection of Loop-Mediated Isothermal Amplification on Paper Microfluidic Chips

        2018

      • μPAD Fluorescence Scattering Immunoagglutination Assay for Cancer Biomarkers from Blood and Serum

        2018

      • Organ-on-a-Chip for Assessing Environmental Toxicants

        2017

      • Rapid and Reliable Norovirus Assay at pg/mL Level Using Smartphone-Based Fluorescence Microscope and a Microfluidic Paper Analytic Device

        2017

      • Smartphone Detection of UV LED Enhanced Particle Immunoassay on Paper Microfluidics

        2017

      • Multi-Normalization and Interpolation Protocol to Improve Norovirus Immunoagglutination Assay from Paper Microfluidics with Smartphone Detection

        2017

      • Towards the 10-Year Milestone of Journal of Biological Engineering

        2017

      • Mie Scatter Spectra-Based Device for Instant, Contact-Free, and Specific Diagnosis of Bacterial Skin Infection

        2017

      • Mie Scatter and Interfacial Tension Based Real-Time Quantification of Colloidal Emulsion Nucleic Acid Amplification

        2017

      • Angular Photodiode Array-Based Device to Detect Bacterial Pathogens in a Wound Model

        2017

      • Immunoagglutinated Particle Rheology Sensing on a Microfluidic Paper-Based Analytical Device for Pathogen Detection

        2017

      • Smartphone-Based Fluorescence Detection of Bisphenol A from Water Samples

        2017

      • Future Developments in Biosensors for Field-Ready Zika Virus Diagnostics

        2017

      • Tuneable Nanoparticle-Nanofiber Composite Substrate for Improved Cellular Adhesion

        2016

      • In Situ, Dual-Mode Monitoring of Organ-on-a-Chip with Smartphone-Based Fluorescence Microscope

        2016

      • Multimodal Imaging and Lighting Bias Correction for Improved uPAD-based Water Quality Monitoring via Smartphones

        2016

      • Recent Approaches for Optical Smartphone Sensing in Resource-Limited Settings: A Brief Review

        2016

      • Use of biosensors in secondary education classroom

        2015

      • Biosensors for Monitoring Airborne Pathogens

        2015

      • Smartphone-based, sensitive uPAD detection of urinary tract infection and gonorrhea

        2015

      • [Invited talk] Smartphone biosensors and organ-on-a-chip

        2015

      • Droplet-Based Immunoassay on a 'Sticky' Nanofibrous Surface for Multiplexed and Double Detection of Bacteria Using Smartphones

        2015

      • Interfacial effects revolutionize qPCR by low threshold cycle detection and inhibition relief

        2015

      • A Portable, Shock-Proof, Surface-Heated Droplet PCR System for Escherichia coli Detection

        2015

      • Smartphone Detection of Escherichia coli from Field Water Samples on Paper Microfluidics

        2015

      • Enhanced nucleic acid amplification with blood in situ by wire-guided droplet manipulation (WDM)

        2014

      • Quantitative, surface heated, droplet polymerase chain reaction for detecting pathogens

        2014

      • Enhanced fluorescent light scatter detection of cancer biomarkers using paper microfluidics

        2014

      • Pro-adhesive extracellular matrix mimic for use in organ-on-a-chip

        2014

      • Rapid molecular diagnosis of infective endocarditis: developing uREx Dx

        2014

      • Paper microfluidic extraction and direct smartphone-based identification of pathogenic nucleic acids from field and clinical samples

        2014

      • Paper Microfluidics for Red Wine Tasting

        2014

      • Rapid, single-step, droplet-based bacterial assay platform on a nanofibrous substrate

        2014

      • Smartphone-Based Optofluidic Lab-on-a-Chip for Detecting Pathogens from Blood

        2014

      • Rapid and Sensitive Detection of H1N1/2009 Virus from Aerosol Samples with a Microfluidic Immunosensor

        2014

      • Fabrication of a pro-adhesive surface using electrospun PCL nanofibers interspersed with peptide conjugated polystyrene particles

        2014

      • Smartphone-Based lab-on-a-chip sensor for flu detection

        2014

      • Rapid and Reagentless Detection of Microbial Contamination within Meat Utilizing a Smartphone-Based Biosensor

        2014

      • Smartphone Detection of Escherichia coli from Wastewater Utilizing Paper Microfluidics

        2013

      • Linear fibroblast alignment on sinusoidal wave micropatterns

        2013

      • Interaction with nanoscale topography: The use of nanowelltrapped charged ligand-bearing nanoparticle surfaces to modulate physiological focal adhesions in endothelial cells

        2013

      • Direct Detection of Plasmid-Mediated Antibiotic Resistance in Bloodstream Infection by PCR Using Wire-Guided Droplet Manipulation (WDM)

        2013

      • Smartphone quantifies Salmonella from paper microfluidics

        2013

      • Nanowell-trapped charged ligand-bearing nanoparticle surfaces: a novel method of enhancing flow-resistant cell adhesion

        2013

      • Shear- vs. nanotopography-guided control of growth of endothelial cells on RGD-nanoparticle-nanowell arrays

        2013

      • Optofluidic lab-on-a-chip monitoring of subsurface bacterial transport

        2013

      • Single-pipetting microfluidic assay device for rapid detection of Salmonella from poultry package

        2013

      • Paper Microfluidic Extraction of Bacterial and Viral Nucleic Acid from Field and Clinical Samples towards a Direct MicroTAS Apparatus

        2013

      • Rapid and Sensitive Detection of Malaria Antigen in Human Blood with Lab-on-a-Chip

        2012

      • Cell-phone-based measurement of TSH using Mie scatter optimized lateral flow assays

        2012

      • Rapid and sensitive detection of malaria antigen in whole blood using a handheld LOC device

        2012

      • Who we are what we can do

        2012

      • Lab-on-a-chip pathogen sensors for food safety

        2012

      • Droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling for simpler and faster PCR assay using wire-guided manipulations

        2012

      • Extremely rapid and fully reprogrammable total PCR assays using wire-guided droplet microfluidics

        2012

      • Single-pipetting microfluidic assay device for Salmonella in poultry package water

        2012

      • Low-level detection of Cryptosporidium parvum in field water using optical microfluidic biosensors

        2012

      • Field-deployable and near-real-time optical microfluidic biosensors for single-oocyst-level detection of Cryptosporidium parvum from field water samples

        2012

      • Sensitive Mie scattering immunoagglutination assay of porcine reproductive and respiratory syndrome virus (PRRSV) from lung tissue samples in a microfluidic chip

        2011

      • Nanoparticle immunoagglutination Rayleigh scatter assay to complement microparticle immunoagglutination Mie scatter assay in a microfluidic device

        2011

      • Direct and sensitive detection of foodborne pathogens within fresh produce samples using a field-deployable handheld device

        2011

      • Very quick reverse transcription polymerase chain reaction for detecting 2009 H1N1 influenza A using wire-guide droplet manipulations

        2011

      • Development of a Handheld Optofluidic Immunosensor to Track the Transport and Distribution of H1N1/2009 Virus in a Mock Classroom

        2011

      • Biosensor detection CS of an airborne mystery disease

        2010

      • Microfluidic immunosensor with integrated liquid core waveguides for sensitive Mie scattering detection of avian influenza antigens in a real biological matrix

        2010

      • Lab-on-a-Chip for Field Escherichia coli Assays: Long-Term Stability of Reagents and Automatic Sampling System

        2010

      • FRET detection of Octamer-4 on a protein nanoarray made by size-dependent self-assembly

        2010

      • Optofluidic device monitoring and fluid dynamics simulation for the spread of viral pathogens in a livestock environment

        2010

      • Detection of avian influenza antigens in proximity fiber, droplet and optical waveguide microfluidics

        2009

      • Size-dependent self-assembly of submicron/nano beads-protein conjugates for construction of a protein nanoarray

        2009

      • Protein nanoarray made by size-dependent self-assembly for detection of mouse immunoglobulin G and octamer-4

        2009

      • Microfluidic immunosensor for rapid and sensitive detection of bovine viral diarrhea virus

        2009

      • Reusable, polyethylene glycol-structured microfluidic channel for particle immunoassays

        2009

      • Real-time detection of Escherichia coli in water pipe using a microfluidic device with one-step latex immunoagglutination assay

        2009

      • Analysis of the thermal environment in a mushroom house using sensible heat balance and 3-D computational fluid dynamics

        2009

      • Grand challenges for biological engineering

        2009

      • Fluorescence resonance energy transfer detection of mouse immunoglobulin G and octamer-4 on protein nanoarray

        2009

      • Single cell level detection of Escherichia coli in microfluidic device

        2008

      • Backscattering particle immunoassays in wire-guide droplet manipulations

        2008

      • Latex immunoagglutination assay for bovine viral diarrhea virus utilizing forward light scattering in a microfluidic device

        2008

      • Latex immunoagglutination assay for a vasculitis marker in a microfluidic device using static light scattering detection

        2007

      • CFD modeling to improve the design of a fog system for cooling greenhouses

        2007

      • Microfluidic device monitoring of waterborne pathogens in model water distribution systems

        2007

      • Lab-on-a-chip immunoassay for multiple antibodies using microsphere light scattering and quantum dot emission

        2007

      • Microfluidic device detection of waterborne pathogens through static light scattering of latex immunoagglutination using proximity optical fibers

        2007

      • The enhanced diffusional mixing for latex immunoagglutination assay in a microfluidic device

        2007

      • Fluorescent biorecognition of gold nanoparticle-IgG conjugates self-assembled on E-beam patterns

        2006

      • Using highly carboxylated microspheres to simplify immunoassays and enhance diffusional mixing in a microfluidic device

        2006

      • Self-assembly of gold nanoparticles on e-beam nano-patterns towards protein nanoarray

        2005

      • Using a stirred cell to evaluate structural changes in proteins adsorbed on particles

        2005

      • Enantioselective discrimination of D-and L-phenylalanine by chiral polyaniline thin films

        2003

      • Preventing biomolecular adsorption in electrowetting-based biofluidic chips

        2003

      • Effect of electrostatic repulsive force on the permeate flux and flux modeling in the microfiltration of negatively charged microspheres

        2003

      • Effects of surface characteristics on non-specific agglutination in latex immunoagglutination antibody assay

        2003

      • Modeling of the permeate flux during microfiltration of BSA-adsorbed microspheres in a stirred cell

        2000

      • The relationship of interaction forces in the protein adsorption onto polymeric microspheres

        1999

      • Continuous separation of serum proteins using a stirred cell charged with carboxylated and sulfonated microspheres

        1998

      • Interpretation of protein adsorption phenomena onto functional microspheres

        1998

      • Optimum growth conditions and pH control solution for PHB biosynthesis in A. eutrophus

        1998

      • Separation of serum proteins with uncoupled microsphere particles in a stirred cell

        1998

      • Adsorption of BSA on highly carboxylated microspheres - Quantitative effects of surface functional groups and interaction forces

        1996

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