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Picture of Haining Zhu

Haining Zhu

Professor, Chemistry and Biochemistry-Sci | Professor, Neuroscience - GIDP | Professor, Pharmacology and Toxicology | Endowed Chair, R Ken and Donna Coit - Aging and Neurodegenerative Diseases | Member of the Graduate Faculty | Professor, Innovations in Aging - GIDP

Pharmacology and Toxicology

Collaboration(14)

Ritu Pandey
Linda Garland
Wei Wang
Pawel Kiela
Juanita Merchant

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Grants(8)

Training in Environmental Toxicology of Human Disease
Active·2024·$0 / $671.6K·
External
environmental toxicology, human disease, training, environmental health, medical education
IPA Assignment Agreement for Megan Carver
Active·2024·$50.4K·
External
Principal Investigator (PI)
intellectual property, contract law, licensing, employment, legal agreements
Biomolecular Condensates in Retinal Degeneration as a Target for Neuroprotection
Active·2023·$366K·
External
Principal Investigator (PI)
biomolecular condensates, retinal degeneration, neuroprotection, biomolecular, retinal
SAVAHCS IPA Assignment Agreement for Chunlong Ma
Active·2022·$272.1K·
External
Principal Investigator (PI)
healthcare, medical billing, insurance, managed care, contract negotiation
SAVAHCS IPA Assignment Agreement for Wen yi Chiu
Active·2022·$264.6K / $132.3K·
External
Principal Investigator (PI)
healthcare, network provider, contractual agreement, medical services, insurance

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Publications(120)

Recent

Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis

2024

prostate cancer, drug resistance, cell cycle

Stress Granules Play a Critical Role in Hexavalent Chromium-Induced Malignancy in a G3BP1 Dependent Manner

2024

malignancy, g3bp1

Long noncoding RNA ABHD11-AS1 interacts with SART3 and regulates CD44 RNA alternative splicing to promote lung carcinogenesis

2024

long noncoding rna

m6A-mediated epi-transcriptomic dysregulation underlies synaptic dysfunction in fragile X syndrome

2024

fragile x syndrome, epigenetics

Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids

2024

organoid modeling, blood-brain barrier, formation

ABL1/2 and DDR1 drive MEKi resistance in NRAS-mutant melanomas by stabilizing RAF/MYC/ETS1 and promoting RAF homodimerization

2023

melanoma, drug resistance, cell signaling, targeted therapy

Mid‐life APOE4 to APOE2 ‘Switching’Alters the Cerebral Transcriptome and Lipidome in a Transgenic Mouse Model

2023

genetics, neuroscience, transcriptomics, lipidomics, aging

Apolipoprotein E proteinopathy is a major dementia-associated pathologic biomarker in individuals with or without the APOE Epsilon 4 Allele

2022

dementia, apolipoprotein e, proteinopathy, biomarker, genetics

Yin and yang regulation of stress granules by Caprin-1

2022

stress granules, yin and yang regulation, caprin-1, regulation, cellular stress response

Broiler genetics influences proteome profiles of normal and woody breast muscle

2021

genetics, proteomics, muscle physiology, poultry farming, muscle disorders