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Tally Largent-Milnes

Associate Professor, BIO5 Institute | Member of the Graduate Faculty | Associate Professor, Pharmacology

Pharmacology
Map Page
60+ Collaborators
$6.3M / $18.2M Funding
10+ Grants
90+ Publications
7+ Courses
5+ Tech/Patents

About

The opioid and chronic pain epidemics go hand in hand; my lab investigates the intersection between the physiology of chronic pain states, analgesic pharmacology, and overcoming the gatekeeper of CNS pharmacology- the blood brain barrier.

Research Area

neuroscience, pain management, drug development, pharmacology, pain, cancer, neuropathic pain, migraine, neuropharmacology, inflammation, animal models, research, chronic pain, endocannabinoid system, glutamate, drug discovery, opioid addiction, bone, bone health, hormones, blood-brain barrier, cell biology, respiratory depression, cell signaling, cannabinoids

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    Recent

    Problems in management of medication overuse headache in transgender and gender non-conforming populations

    2024

    Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache

    2024
    formoterol, headache, neuropharmacology

    Utilizing the Human Proteome and Phospho Proteome as a2 Biomarker for Migraine, a Pilot Study

    2024

    Activating transcription factor 3 ATF3) and calcitonin gene-related peptide CGRP) increase in trigeminal ganglion neurons in female rats after photorefractive keratectomy PRK)like corneal abrasion

    2024

    It's Legal: Now What? Development, Implementation, and Impact of Interprofessional Cannabis Education

    2024

    Isolation and monoculture of functional primary astrocytes from the adult mouse spinal cord

    2024
    neuroscience, cell culture, astrocytes, spinal cord, mouse model

    The endocannabinoid system and breathing

    2023
    neuroscience, respiratory physiology, pharmacology, endocannabinoid system, medical physiology

    PNA6, a Lactosyl Analogue of Angiotensin-1-7) Reverses Pain Induced in Murine Models of Inflammation, Chemotherapy-Induced Peripheral Neuropathy, and Metastatic Bone Disease

    2023
    pain relief, inflammation, chemotherapy, peripheral neuropathy, metastatic bone disease

    Morphine-induced osteolysis and hypersensitivity is mediated through toll-like receptor-4 in a murine model of metastatic breast cancer

    2023
    pain, cancer, inflammation, bone, immunology

    Molecular mechanisms of hormones implicated in migraine and the translational implication for transgender patients

    2023
    migraine, hormones, transgender health, molecular mechanisms, translational medicine

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    • Pain

    • Molecular Targets of Pharmacological Agents

    • Pharmacology: General Principles

    • Introduction to Pharmacology

    • Neuropharmacolgy

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    Tally Largent-Milnes | KMap Profile - Institutional Knowledge Map (KMap)