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M. Leandro Heien
Associate Professor, Chemistry and Biochemistry-Sci | Member of the Graduate Faculty
Chemistry & Biochemistry - Sci
Map Page
Research Area
neuroscience,
parkinson's disease,
electrochemistry,
analytical chemistry,
dopamine,
ketamine,
mechanisms,
treatment,
low-dose,
catecholamines
Grants
(9)
The Center of Excellence in Addiction Studies (CEAS)
Active
·
2021
·
$444.5K / $5.3M
·
External
Co-Investigator (COI)
addiction studies,
substance abuse,
mental health,
behavioral interventions,
neuroscience
Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease
Active
·
2021
·
$44.5K / $1.6M
·
External
Co-Investigator (COI)
parkinson's disease,
ketamine,
mechanisms,
treatment,
low-dose
Control of the Time Course of Dopamine Release Through Optimized Electrical Brain Stimulation
Active
·
2021
·
$734.6K / $1.5M
·
External
Multiple Principal Investigator (MPI)
neuromodulation,
dopamine,
brain stimulation,
neuroscience,
control
Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease
2019
·
$19.3K / $385.1K
·
External
Co-Investigator (COI)
ketamine,
parkinson's disease,
mechanisms,
treatment,
low-dose
Development of Advanced Voltammetric Method for Basal Neurotransmitter Level Measurement
2019
·
$236K
·
External
Principal Investigator (PI)
neuroscience,
electrochemistry,
analytical chemistry,
biosensors,
neuropharmacology
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Publications
(55)
Recent
Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells
2014
neuroscience,
cell biology,
endocrinology,
hormones,
signal transduction
Microwave-plasma dry-etch for fabrication of conducting polymer microelectrodes
2014
plasma etching,
conducting polymers,
microfabrication,
microwave processing,
electrode fabrication
Electrochemical generation of hydroxyl radicals for examining protein structure
2013
electrochemistry,
protein structure,
hydroxyl radicals,
chemical biology,
analytical chemistry
Rethinking data collection and signal processing. 2. Preserving the temporal fidelity of electrochemical measurements
2013
data collection,
signal processing,
electrochemical measurements,
temporal fidelity,
research methods
The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry
2013
neuroscience,
catecholamines,
secretory vesicles,
cns,
electrochemical cytometry
Fast-scan controlled-adsorption voltammetry for the quantification of absolute concentrations and adsorption dynamics
2013
voltammetry,
adsorption,
concentration,
scan,
dynamics
Oral administration of methylphenidate blocks the effect of cocaine on uptake at the drosophila dopamine transporter
2013
neuroscience,
pharmacology,
drug abuse,
toxicology,
behavioral science
Characterization of poly(3,4-ethylenedioxythiophene)Tosylate conductive polymer microelectrodes for transmitter detection
2012
Rethinking data collection and signal processing. 1. Real-time oversampling filter for chemical measurements
2012
Monitoring extracellular pH, oxygen, and dopamine during reward delivery in the striatum of primates
2012
Collaborations
(34)
Helena Morrison
Mutual work: 2 Grants﹒2 Publications﹒3 Proposals
Collaboration Details
David Besselsen
Mutual work: 3 Publications
Collaboration Details
Todd Vanderah
Mutual work: 1 Grant﹒9 Proposals﹒2 Publications
Collaboration Details
John Konhilas
Mutual work: 3 Proposals
Collaboration Details
Scott Sherman
Mutual work: 3 Grants﹒16 Proposals﹒22 Publications
Collaboration Details
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Courses
(8)
Analytical Separations
Advanced Analytical Chemistry
Instrumental Analysis
Biochemistry
Mass Spectrometry
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Techs/Patents
(19)
Glycopeptide-Lipid Supramolecular Assembly
2023
·
Technology
Portable Instrument For Field Ready Electrochemical Experimentation
2022
·
Patent
Micelles And Vesicles For The Delivery Of Glycopeptides
2022
·
Patent
Collection and Processing of Analytical Data
2021
·
Patent
Glycosylated Peptides With Pseudoproline Residues And Having Enhanced Half-Lives And Ability To Cross The Blood Brain Barrier
2020
·
Patent
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30+ Collaborators
$2.8M / $14.5M Funding
8+ Grants
50+ Publications
7+ Courses
10+ Tech/Patents
