Courses
- ASAnalytical Separations
- AACAdvanced Analytical Chemistry
- BCBioanalytical Chemistry
- BBiochemistry
- AACAdvanced Analytical Chemistry Laboratory
- ACAnalytical Chemistry
- MSMass Spectrometry
- IAInstrumental Analysis
Grants
- The Center of Excellence in Addiction Studies (CEAS)
Co-Investigator (COI)
2021
$2.6MActive - Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease
Co-Investigator (COI)
2021
$1.2MActive - Control of the Time Course of Dopamine Release Through Optimized Electrical Brain Stimulation
Multiple Principal Investigator (MPI)
2021
$1.1MActive - Development of Advanced Voltammetric Method for Basal Neurotransmitter Level Measurement
Principal Investigator (PI)
2019
$236.0KActive - Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease
Co-Investigator (COI)
2019
$385.1K - Cortical Opioid Dysfunction in Chronic Pain
Co-Investigator (COI)
2016
$2.7M - PACAP/VIP Glycopeptide Agonists as Neuroprotective Therapies for Parkinson's Disease
Co-Investigator (COI)
2015
$2.0M - Direct Measurements of Neurotransmitter Concentrations in Vivo
Principal Investigator (PI)
2014
$392.6K - BRAIN EAGER:Integrated Measurement of Dopamine Release and Large-Scale Ensemble Activity in Behaving Animals
Co-Investigator (COI)
2014
$299.5K
Technologies / Patents
Publications (55)
Recent
- Microwave-plasma dry-etch for fabrication of conducting polymer microelectrodes
2014
- Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells
2014
- Rethinking data collection and signal processing. 2. Preserving the temporal fidelity of electrochemical measurements
2013
- Oral administration of methylphenidate blocks the effect of cocaine on uptake at the drosophila dopamine transporter
2013
- Electrochemical generation of hydroxyl radicals for examining protein structure
2013
- The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry
2013
- Fast-scan controlled-adsorption voltammetry for the quantification of absolute concentrations and adsorption dynamics
2013
- Amperometric noise at thin film band electrodes
2012
- Rethinking data collection and signal processing. 1. Real-time oversampling filter for chemical measurements
2012
- Monitoring extracellular pH, oxygen, and dopamine during reward delivery in the striatum of primates
2012
- Characterization of poly(3,4-ethylenedioxythiophene)Tosylate conductive polymer microelectrodes for transmitter detection
2012
- Trends in computational simulations of electrochemical processes under hydrodynamic flow in microchannels
2011
- Temporal resolution in electrochemical imaging on single PC12 cells using amperometry and voltammetry at microelectrode Arrays
2011
- Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor
2010
- Mass spectrometry imaging of mating Tetrahymena show that changes in cell morphology regulate lipid domain formation
2010
- Erratum to Multivariate concentration determination using principal component regression with residual analysis Trends Anal. Chem. 28 2009) 1127-1136] DOI:10.1016/j.trac.2009.07.002)
2010
- Analytical approaches to investigate transmitter content and release from single secretory vesicles
2010
- Nanotome Cluster Bombardment to Recover Spatial Chemistry After Preparation of Biological Samples for SIMS Imaging
2010
- Only a fraction of quantal content is released during exocytosis as revealed by electrochemical cytometry of secretory vesicles
2010
- Lipid detection, identification, and imaging single cells with SIMS
2010
- Steady-state electrochemical determination of lipidie nanotube diameter utilizing an artificial cell model
2010
- Probing Exocytosis at Single Cells Using Electrochemistry
2010
- Polymeric crowding agents improve passive biomacromolecule encapsulation in lipid vesicles
2010
- Using in vivo electrochemistry to study the physiological effects of cocaine and other stimulants on the Drosophila melanogaster dopamine transporter
2010
- Multivariate concentration determination using principal component regression with residual analysis
2009
- Hybrid capillary-microfluidic device for the separation, lysis, and electrochemical detection of vesicles
2009
- In vivo electrochemical measurements of exogenously applied dopamine in Drosophila melanogaster
2009
- Textural guidance cues for controlling process outgrowth of mammalian neurons
2009
- Chemical measurements in Drosophila
2009
- Quantitative chemical analysis of single cells.
2009
- Temporal analysis of protozoan lysis in a microfluidic device
2009
- Time-of-flight secondary ion mass spectrometry imaging of subcellular lipid heterogeneity: Poisson counting and spatial resolution
2009
- Amperometric measurements of catecholamine release from single vesicles in MN9D cells
2008
- MS/MS methodology to improve subcellular mapping of cholesterol using TOF-SIMS
2008
- Spatially and temporally resolved single-cell exocytosis utilizing individually addressable carbon microelectrode arrays
2008
- Freeze-etching and vapor matrix deposition for ToF-SIMS imaging of single cells
2008
- Solution to the neurochemical challenge
2007
- Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation
2007
- Mass spectrometric imaging of the nervous system
2007
- Mass spectrometric imaging of peptide release from neuronal cells within microfluidic devices
2007
- Coordinated Accumbal Dopamine Release and Neural Activity Drive Goal-Directed Behavior
2007
- Neurochemical challenge
2007
- Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens
2007
- Phasic dopamine signaling during behavior, reward, and disease states
2006
- Simultaneous dopamine and single-unit recordings reveal accumbens GABAergic responses: Implications for intracranial self-stimulation
2005
- Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats
2005
- Resolving neurotransmitters detected by fast-scan cyclic voltammetry
2004
- Cannabinoids Enhance Subsecond Dopamine Release in the Nucleus Accumbens of Awake Rats
2004
- Voltammetric detection of metal nanoparticles separated by liquid chromatography
2004
- Probing electric fields inside microfluidic channels during electroosmotic flow with fast-scan cyclic voltammetry
2004
- Erratum: Subsecond dopamine release promotes cocaine seeking Nature 2003) 422 614-618)
2003
- Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo
2003
- Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity
2003
- Frequency of dopamine concentration transients increases in dorsal and ventral striatum of male rats during introduction of conspecifics
2002
- Neurochemistry and electroanalytical probes
2002
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