KMap
Courses
  • AS
    Analytical Separations

  • AAC
    Advanced Analytical Chemistry

  • BC
    Bioanalytical Chemistry

  • B
    Biochemistry

  • AAC
    Advanced Analytical Chemistry Laboratory

  • AC
    Analytical Chemistry

  • MS
    Mass Spectrometry

  • IA
    Instrumental Analysis

Grants
  • Funding agency logo
    The Center of Excellence in Addiction Studies (CEAS)

    Co-Investigator (COI)

    2021

    $2.6M
    Active
  • Funding agency logo
    Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease

    Co-Investigator (COI)

    2021

    $1.2M
    Active
  • Funding agency logo
    Control of the Time Course of Dopamine Release Through Optimized Electrical Brain Stimulation

    Multiple Principal Investigator (MPI)

    2021

    $1.1M
    Active
  • Funding agency logo
    Development of Advanced Voltammetric Method for Basal Neurotransmitter Level Measurement

    Principal Investigator (PI)

    2019

    $236.0K
    Active
  • Funding agency logo
    Mechanisms of Low-Dose Ketamine Treatment for Parkinson's Disease

    Co-Investigator (COI)

    2019

    $385.1K
  • Funding agency logo
    Cortical Opioid Dysfunction in Chronic Pain

    Co-Investigator (COI)

    2016

    $2.7M
  • Funding agency logo
    PACAP/VIP Glycopeptide Agonists as Neuroprotective Therapies for Parkinson's Disease

    Co-Investigator (COI)

    2015

    $2.0M
  • Funding agency logo
    Direct Measurements of Neurotransmitter Concentrations in Vivo

    Principal Investigator (PI)

    2014

    $392.6K
  • Funding agency logo
    BRAIN EAGER:Integrated Measurement of Dopamine Release and Large-Scale Ensemble Activity in Behaving Animals

    Co-Investigator (COI)

    2014

    $299.5K
Technologies / Patents
      Publications (55)
      Recent
      • Microwave-plasma dry-etch for fabrication of conducting polymer microelectrodes

        2014

      • Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells

        2014

      • Rethinking data collection and signal processing. 2. Preserving the temporal fidelity of electrochemical measurements

        2013

      • Oral administration of methylphenidate blocks the effect of cocaine on uptake at the drosophila dopamine transporter

        2013

      • Electrochemical generation of hydroxyl radicals for examining protein structure

        2013

      • The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical cytometry

        2013

      • Fast-scan controlled-adsorption voltammetry for the quantification of absolute concentrations and adsorption dynamics

        2013

      • Amperometric noise at thin film band electrodes

        2012

      • Rethinking data collection and signal processing. 1. Real-time oversampling filter for chemical measurements

        2012

      • Monitoring extracellular pH, oxygen, and dopamine during reward delivery in the striatum of primates

        2012

      • Characterization of poly(3,4-ethylenedioxythiophene)Tosylate conductive polymer microelectrodes for transmitter detection

        2012

      • Temporal resolution in electrochemical imaging on single PC12 cells using amperometry and voltammetry at microelectrode Arrays

        2011

      • Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor

        2010

      • Mass spectrometry imaging of mating Tetrahymena show that changes in cell morphology regulate lipid domain formation

        2010

      • Analytical approaches to investigate transmitter content and release from single secretory vesicles

        2010

      • Nanotome Cluster Bombardment to Recover Spatial Chemistry After Preparation of Biological Samples for SIMS Imaging

        2010

      • Only a fraction of quantal content is released during exocytosis as revealed by electrochemical cytometry of secretory vesicles

        2010

      • Lipid detection, identification, and imaging single cells with SIMS

        2010

      • Steady-state electrochemical determination of lipidie nanotube diameter utilizing an artificial cell model

        2010

      • Probing Exocytosis at Single Cells Using Electrochemistry

        2010

      • Polymeric crowding agents improve passive biomacromolecule encapsulation in lipid vesicles

        2010

      • Using in vivo electrochemistry to study the physiological effects of cocaine and other stimulants on the Drosophila melanogaster dopamine transporter

        2010

      • Multivariate concentration determination using principal component regression with residual analysis

        2009

      • Hybrid capillary-microfluidic device for the separation, lysis, and electrochemical detection of vesicles

        2009

      • In vivo electrochemical measurements of exogenously applied dopamine in Drosophila melanogaster

        2009

      • Textural guidance cues for controlling process outgrowth of mammalian neurons

        2009

      • Chemical measurements in Drosophila

        2009

      • Quantitative chemical analysis of single cells.

        2009

      • Temporal analysis of protozoan lysis in a microfluidic device

        2009

      • Time-of-flight secondary ion mass spectrometry imaging of subcellular lipid heterogeneity: Poisson counting and spatial resolution

        2009

      • Amperometric measurements of catecholamine release from single vesicles in MN9D cells

        2008

      • MS/MS methodology to improve subcellular mapping of cholesterol using TOF-SIMS

        2008

      • Spatially and temporally resolved single-cell exocytosis utilizing individually addressable carbon microelectrode arrays

        2008

      • Freeze-etching and vapor matrix deposition for ToF-SIMS imaging of single cells

        2008

      • Solution to the neurochemical challenge

        2007

      • Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation

        2007

      • Mass spectrometric imaging of the nervous system

        2007

      • Mass spectrometric imaging of peptide release from neuronal cells within microfluidic devices

        2007

      • Coordinated Accumbal Dopamine Release and Neural Activity Drive Goal-Directed Behavior

        2007

      • Neurochemical challenge

        2007

      • Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens

        2007

      • Phasic dopamine signaling during behavior, reward, and disease states

        2006

      • Simultaneous dopamine and single-unit recordings reveal accumbens GABAergic responses: Implications for intracranial self-stimulation

        2005

      • Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats

        2005

      • Resolving neurotransmitters detected by fast-scan cyclic voltammetry

        2004

      • Cannabinoids Enhance Subsecond Dopamine Release in the Nucleus Accumbens of Awake Rats

        2004

      • Voltammetric detection of metal nanoparticles separated by liquid chromatography

        2004

      • Probing electric fields inside microfluidic channels during electroosmotic flow with fast-scan cyclic voltammetry

        2004

      • Erratum: Subsecond dopamine release promotes cocaine seeking Nature 2003) 422 614-618)

        2003

      • Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo

        2003

      • Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity

        2003

      • Frequency of dopamine concentration transients increases in dorsal and ventral striatum of male rats during introduction of conspecifics

        2002

      • Neurochemistry and electroanalytical probes

        2002

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