Kathleen Rodgers

Professor, BIO5 Institute | Professor, Clinical Translational Sciences | Associate Director, Translational Neuroscience | Professor, Pharmacology | Member of the Graduate Faculty

Pharmacology

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50+ Collaborators

$25.7M / $113.8M Funding

Research Area

alzheimer's disease, aging, neuroscience, alzheimer's, cognitive impairment, rasrx1902, pharmacokinetics, regenerative therapy, renin-angiotensin system, medical research, precision medicine, neurodegeneration, endothelial progenitor cells, neurodegenerative diseases, allopregnanolone, drug development, brain aging

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Recent

Vivaria housing conditions expose sex differences in brain oxidation, microglial activation, and immune system states in aged hAPOE4 mice

2024

neuroscience, aging, immunology, animal behavior, oxidative stress

Blood pressure variability, central autonomic network dysfunction and cerebral small vessel disease in APOE4 carriers

2023

blood pressure, autonomic network, cerebral small vessel disease, apoe4 carriers, central nervous system

Blood-Derived Progenitor Cells Are Depleted in Older Adults with Cognitive Impairment: A Role for Vascular Resilience?

2023

aging, cognitive impairment, progenitor cells, vascular resilience, blood

A tale of two systems: Lessons learned from mid-life aging with implications for Alzheimer’s Prevention and Treatment

2022

aging, alzheimer's, prevention, treatment, lessons

Association between menopausal hormone therapy and risk of neurodegenerative diseases: Implications for precision hormone therapy.

2021

menopausal hormone therapy, neurodegenerative diseases, precision hormone therapy, association, risk

Increased Levels of Circulating Angiogenic Cells and Signaling Proteins in Older Adults with Cerebral Small Vessel Disease.

2021

angiogenic cells, cerebral small vessel disease, aging, g-protein signaling, circulating levels

Safety, tolerability and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer’s disease: A phase 1 single and multiple ascending dose clinical phase 1b/2a trial

2020

alzheimer's disease, pharmacokinetics, safety, regenerative therapeutic, clinical trial

Hormone Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes: A Retrospective Patient Cohort Analysis

2020

cancer, neurodegeneration, hormones, therapies, retrospective analysis

Targeting the Renin-Angiotensin System to Reduce Systemic Lupus Erythematosus Related Pathologies in MRL-lpr Mice

2020

renin-angiotensin system, systemic lupus erythematosus, mrl-lpr mice, pathologies, targeting therapy

Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain

2020

neuropathic pain, transgenic mice, sumoylation, nav1.7 regulation, sex-specific regulation

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Problem Based Translational Research in Alzheimer's Disease and Related Dementias I
Problem Based Translational Research in Alzheimer's Disease and Related Dementias II

Novel Mouse Strain for Inflammation and Neurodegeneration
2024·Technology
Methods For Treating Or Limiting Development Of Cardiovascular Disease-Related Neurological Disorders
2023·Patent
Treatment of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) with a Polypeptide
2020·Technology
Development of Aptamers Neutralizing Antibodies for Demyelinating Diseases
2018·Technology
Agents, Compositions And Methods For Treating And Preventing Alzheimer’s Disease
1899·Patent

Kathleen Rodgers

Research Area

Grants(29)

Publications(22)

Vivaria housing conditions expose sex differences in brain oxidation, microglial activation, and immune system states in aged hAPOE4 mice

Blood pressure variability, central autonomic network dysfunction and cerebral small vessel disease in APOE4 carriers

Blood-Derived Progenitor Cells Are Depleted in Older Adults with Cognitive Impairment: A Role for Vascular Resilience?

A tale of two systems: Lessons learned from mid-life aging with implications for Alzheimer’s Prevention and Treatment

Association between menopausal hormone therapy and risk of neurodegenerative diseases: Implications for precision hormone therapy.

Increased Levels of Circulating Angiogenic Cells and Signaling Proteins in Older Adults with Cerebral Small Vessel Disease.

Safety, tolerability and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer’s disease: A phase 1 single and multiple ascending dose clinical phase 1b/2a trial

Hormone Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes: A Retrospective Patient Cohort Analysis

Targeting the Renin-Angiotensin System to Reduce Systemic Lupus Erythematosus Related Pathologies in MRL-lpr Mice

Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain

Collaborations(52)

Sairam Parthasarathy

Kenneth Knox

Teshia Solomon

Jarrod Mosier

Bonnie LaFleur

News(5)

NIH Grant Advances Research on Women's Brains, Menopause and Alzheimer's Risk

Despite COVID, UArizona Reports Strong Year for Innovation and Commercialization

One Small Molecule, Potential Giant Step to Improve Cognitive Function

Developing a Diverse Workforce To End the Alzheimer’s Epidemic

Building a Pathway from Tribal College to Neuroscience Laboratories

Courses(2)

Problem Based Translational Research in Alzheimer's Disease and Related Dementias I

Problem Based Translational Research in Alzheimer's Disease and Related Dementias II

Techs/Patents(5)

Novel Mouse Strain for Inflammation and Neurodegeneration

Treatment of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) with a Polypeptide

Development of Aptamers Neutralizing Antibodies for Demyelinating Diseases

Agents, Compositions And Methods For Treating And Preventing Alzheimer’s Disease