Scaffolds are three-dimensional structures or materials that are used in tissue engineering and regenerative medicine to support the growth and development of cells and tissues. These scaffolds provide a framework for cells to attach, proliferate, and organize into functional tissue structures. They mimic the natural extracellular matrix found in the body and provide mechanical and structural support to guide tissue regeneration. Scaffolds can be made from a variety of materials, including natural polymers, synthetic polymers, ceramics, and composites, and can be designed with specific properties to promote tissue growth and regeneration in various applications, such as bone, cartilage, skin, and organs. Research in this area focuses on developing novel scaffold materials and fabrication techniques to improve tissue regeneration outcomes and advance the field of regenerative medicine.