Biographical Sketch for John A. Szivek, Ph.D. Dr. Szivek was educated in Toronto, Canada where he completed his PhD. His research topic was a study of the nature of activity induced bone formation and the study of bone loss around orthopedic implants. Dr. Szivek moved to the University of Arizona in the fall of 1990 where he was appointed to direct the Orthopedic Research Laboratory, in the Department of Surgery at the College of Medicine. He is a senior researcher in the Arizona Arthritis Center and in 2003 was awarded the William and Sylvia Rubin Chair in Orthopaedic Research by the Department of Orthopaedic Surgery to support his studies on cartilage regeneration and in vivo load sensing. The Center has scientists from a number of disciplines working together at the University of Arizona to develobetter treatment for persons suffering from arthritis. Dr. Szivek has had a number of federal and private grants to study the effect of exercise on bone and cartilage and to measure loads acting on healthy musculoskeletal tissues to better understand osteoarthritis and potential treatments for patients with osteoarthritis.