The University of Arizona
Map Home
Adjust height of sidebar
KMap

Topic:kinases

kinases

Since 2021, aggregated from related topics

About

    Kinases are enzymes that play a crucial role in the regulation of various cellular processes by catalyzing the transfer of phosphate groups from ATP to target proteins, thereby altering their function, activity, or localization within the cell. They are key components of signal transduction pathways and are involved in diverse physiological functions such as cell growth, proliferation, differentiation, and apoptosis. Dysregulation of kinase activity has been implicated in numerous diseases, including cancer, inflammation, and metabolic disorders, making them important targets for drug development. Kinase inhibitors have shown promise in the treatment of various cancers and other diseases, and ongoing research in this area aims to further understand the role of kinases in cellular signaling and disease progression.

Related Topics

People

View more people