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Picture of Rayna Gonzales

Rayna Gonzales

Member of the Graduate Faculty | Associate Professor, Translational Neuroscience | Associate Professor, Clinical Translational Sciences | Associate Professor, Basic Medical Sciences

College of Medicine - Phoenix

Collaboration(19)

Melissa Herbst-Kralovetz
Shenfeng Qiu
Taben Hale
Amelia Gallitano
Jason Karnes

Page 1 of 4

Grants(5)

Oxytocin Sensitivity and Postpartum Hemorrhage: Testing Genetic and Epigenetic Biomarkers for Improving Maternal Morbidity
Active·2023·$216.5K / $288.6K·
External
Key Personnel (KP)
oxytocin, genetic biomarkers, epigenetic biomarkers, postpartum hemorrhage, maternal morbidity
PVAHCS IPA Rayna Gonzales
Active·2021·$15.2K·
External
Principal Investigator (PI)
healthcare, medical research, clinical services, patient care, administrative services
Contribution of Selective Vascular S1PR Type 1 Modulation during Acute Ischemic Stroke
2019·$154K·
External
Principal Investigator (PI)
stroke, vascular, s1pr type 1, ischemic, modulation
Probing the Mechanistic Role of Vascular Dysfunction and Vascular Inflammation in TBI-Mediated Cognitive Dysfunction
2017·$113.9K / $569.4K·
External
Co-Investigator (COI)
vascular dysfunction, vascular inflammation, tbi-mediated cognitive dysfunction, mechanistic role, research
Influence of Local Testosterone Aromatization on Angiotesin-Induced Vascular Remodeling
2013·$0 / $140K·
External
Co-Investigator (COI)
hormone regulation, vascular remodeling, testosterone metabolism, angiotensin signaling, hormone-induced vascular changes

Publications(66)

Recent

LOX-1 and MMP-9 inhibition attenuate the detrimental effects of delayed rt-PA therapy and improve outcome after acute ischemic stroke

2023

ischemic stroke, therapy, lox-1 inhibition, mmp-9 inhibition, outcome improvement

Doxorubicin modulates proinflammatory mediator expression in the rodent vasculature during high intense exercise

2023

doxorubicin, vascular inflammation, exercise physiology, proinflammatory mediators, rodent model

LOX-1 expression and the differential vasoactive effects of oxLDL/LOX-1 in female and male mouse thoracic aorta.

2023

cardiovascular, gender differences, oxidized ldl, vascular biology, gene expression

Elevated Levels of Particulate Matter 2.5 and Ischemic Injury Induces Human Brain Microvascular Endothelial Barrier Dysfunction and Inflammation.

2023

particulate matter, ischemic injury, brain microvascular, endothelial barrier, inflammation

Doxorubicin temporally alters cyclooxygenase-2 expression in human vascular smooth muscle cells

2023

chemotherapy, vascular health, gene expression, drug effects, smooth muscle cells

Differential LOX-1 splice variant expression and detrimental role of oxLDL on vascular smooth muscle and endothelium in human aorta and brain vasculature.

2023

vascular biology, cardiovascular disease, gene expression, atherosclerosis, smooth muscle cells

Ozanimod Differentially Preserves Human Cerebrovascular Endothelial Barrier Proteins and Attenuates MMP-9 Activity Following In Vitro Acute Ischemic Injury

2023

ischemic injury, cerebrovascular endothelial, ozanimod, barrier proteins, mmp-9 activity

Nanoparticle Containing BDNF-mimetic Improves Brain Endothelial Cell Barrier Properties Following Acute Ischemia Reperfusion-like Injury

2023

nanoparticles, brain endothelial cells, bdnf-mimetic, ischemia, reperfusion injury

Ozanimod Attenuates Human Cerebrovascular Endothelial Derived MMP-9 Activity and Preserves Barrier Properties Following In Vitro Acute Ischemic Injury

2023

ischemic injury, cerebrovascular endothelial, mmp-9 activity, ozanimod, barrier properties

Endogenous Androgens via Selective Estrogen Receptor Beta Activation Protects Against Ischemia/Reperfusion Injury in an Adult Experimental Stroke Mouse Model

2023

androgens, estrogen receptor beta, ischemia, reperfusion injury, stroke