Ischemia is a condition in which there is an inadequate blood supply to a part of the body, typically due to a blockage in the arteries. This lack of blood flow can result in tissue damage and cell death if not treated promptly. Ischemia can occur in various parts of the body, including the heart, brain, and limbs, and can lead to serious health complications such as heart attacks, strokes, and limb amputations. Research in the area of ischemia focuses on understanding the underlying causes of this condition, developing effective treatments to restore blood flow, and preventing long-term damage to affected tissues.