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Profile
Melissa Halpern
Associate Professor
Pediatrics
Overview
Research
More
Collaboration
(10)
Fayez Ghishan
Mutual work: 1 Grant﹒1 Proposal
Collaboration Details
Nathan Cherrington
Mutual work: 1 Grant﹒1 Publication
Collaboration Details
Sheila Gephart
Mutual work: 1 Proposal﹒1 Publication﹒1 Grant
Collaboration Details
Dean Billheimer
Mutual work: 2 Proposals
Collaboration Details
Janet Rothers
Mutual work: 1 Proposal﹒2 Publications﹒1 Grant
Collaboration Details
Page 1 of 2
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Grants
(7)
Bile Acids in Necrotizing Enterocolitis
Active
·
2018
·
$1.4M / $1.9M
·
External
Principal Investigator (PI)
gut health,
pediatrics,
biomarkers,
intestinal inflammation,
neonatal health
Assessing Variation in Fecal Bile Acids as a Novel Early Indicator of Necrotizing Enterocolitis
2024
·
$3.9M / $638.8K
·
External
Principal Investigator (PI)
gut health,
bile acids,
necrotizing enterocolitis,
early detection,
microbiome
Bile Acids as a Biomarker to Predict Development of Necrotizing Enterocolitis
2014
·
$395.8K / $416.6K
·
External
Principal Investigator (PI)
biomarkers,
necrotizing enterocolitis,
bile acids,
development,
predictive medicine
ASBT Inhibitor in NEC
2012
·
$37.7K
·
External
Principal Investigator (PI)
gastrointestinal,
enzyme inhibition,
pediatrics,
biomedical,
drug development
Validating a Necrotizing Enterocolitis (NEC) Risk Index for Neonates
2011
·
$0 / $31.3K
·
External
Co-Investigator (COI)
neonatal diseases,
medical diagnosis,
risk assessment,
pediatrics,
clinical prediction models
Page 1 of 2
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Publications
(77)
Recent
exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter
2024
necrotizing enterocolitis,
bile acid transporter,
experimental exacerbation,
apical upregulation,
intestinal inflammation
Pulsitile exposure to bile acids alters tight junction proteins in mouse enteroids.
2023
intestinal health,
bile acids,
intestinal barrier,
digestive system,
cellular response
Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter.
2023
clostridium scindens,
necrotizing enterocolitis,
bile acid transporter,
intestinal inflammation,
microbiota dysbiosis
Enteral Feeding and Antibiotic Treatment Do Not Influence Increased Coefficient of Variation of Total Fecal Bile Acids in Necrotizing Enterocolitis.
2023
enteral feeding,
antibiotic treatment,
necrotizing enterocolitis,
fecal bile acids,
treatment influence
Su143 SECONDARY BILE ACID PRODUCER CLOSTRIDIUM SCINDENS EXACERBATES NECROTIZING ENTEROCOLITIS IN NEONATAL RATS
2021
clostridium scindens,
necrotizing enterocolitis,
secondary bile acid,
neonatal rats,
exacerbates
Elevated Coefficient of Variation in Total Fecal Bile Acids Precedes Diagnosis of Necrotizing Enterocolitis.
2020
bile acids,
necrotizing enterocolitis,
diagnosis,
fecal,
elevated coefficient
Su1242 A TWO DIMENSIONAL ENTEROID MODEL TO STUDY THE ROLE OF ASBT IN NECROTIZING ENTEROCOLITIS
2020
enteroid models,
necrotizing enterocolitis,
asbt role,
intestinal diseases,
research methods
The role of intestinal epithelial barrier function in the development of NEC
2015
intestinal epithelial barrier,
nec development,
intestinal health,
immune response,
microbiota interaction
The role of intestinal epithelial barrier function in the development of NEC.
2015
intestinal epithelium,
nec,
barrier function,
intestinal health,
development
Discrimination of GutCheck(NEC) a clinical risk index for necrotizing enterocolitis.
2014
gut health,
medical diagnosis,
clinical risk assessment,
necrotizing enterocolitis,
discrimination