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Melissa Halpern
Associate Professor, Pediatrics - (Research Scholar Track)
Pediatrics
Full Page
Overview
Research
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Collaboration
(7)
Sheila Gephart
Mutual work: 1 Grant﹒1 Proposal﹒1 Publication
Collaboration Details
David Besselsen
Mutual work: 1 Publication
Collaboration Details
Nathan Cherrington
Mutual work: 1 Publication﹒1 Grant
Collaboration Details
Dean Billheimer
Mutual work: 2 Proposals
Collaboration Details
Fayez Ghishan
Mutual work: 1 Grant﹒1 Proposal
Collaboration Details
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Grants
(7)
Assessing Variation in Fecal Bile Acids as a Novel Early Indicator of Necrotizing Enterocolitis
Active
·
2024
·
$562.1K / $638.8K
·
External
Principal Investigator (PI)
gut health,
bile acids,
necrotizing enterocolitis,
early detection,
microbiome
Bile Acids in Necrotizing Enterocolitis
2018
·
$1.4M / $1.9M
·
External
Principal Investigator (PI)
gut health,
pediatrics,
biomarkers,
intestinal inflammation,
neonatal health
Bile Acids as a Biomarker to Predict Development of Necrotizing Enterocolitis
2014
·
$395.8K / $416.6K
·
External
Principal Investigator (PI)
biomarkers,
necrotizing enterocolitis,
bile acids,
development,
predictive medicine
ASBT Inhibitor in NEC
2012
·
$37.7K
·
External
Principal Investigator (PI)
gastrointestinal,
enzyme inhibition,
pediatrics,
biomedical,
drug development
Validating a Necrotizing Enterocolitis (NEC) Risk Index for Neonates
2011
·
$0 / $31.3K
·
External
Co-Investigator (COI)
neonatal diseases,
medical diagnosis,
risk assessment,
pediatrics,
clinical prediction models
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Publications
(68)
Recent
Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter
2024
clostridium scindens,
necrotizing enterocolitis,
bile acid transporter,
upregulation,
experimental
Enteral Feeding and Antibiotic Treatment Do Not Influence Increased Coefficient of Variation of Total Fecal Bile Acids in Necrotizing Enterocolitis.
2023
enteral feeding,
antibiotic treatment,
necrotizing enterocolitis,
fecal bile acids,
treatment influence
Pulsitile exposure to bile acids alters tight junction proteins in mouse enteroids.
2023
intestinal health,
bile acids,
intestinal barrier,
digestive system,
cellular response
Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter.
2023
clostridium scindens,
necrotizing enterocolitis,
bile acid transporter,
intestinal inflammation,
microbiota dysbiosis
Su143 SECONDARY BILE ACID PRODUCER CLOSTRIDIUM SCINDENS EXACERBATES NECROTIZING ENTEROCOLITIS IN NEONATAL RATS
2021
clostridium scindens,
necrotizing enterocolitis,
secondary bile acid,
neonatal rats,
exacerbates
Su1242 A TWO DIMENSIONAL ENTEROID MODEL TO STUDY THE ROLE OF ASBT IN NECROTIZING ENTEROCOLITIS
2020
enteroid models,
necrotizing enterocolitis,
asbt role,
intestinal diseases,
research methods
Elevated Coefficient of Variation in Total Fecal Bile Acids Precedes Diagnosis of Necrotizing Enterocolitis
2020
necrotizing enterocolitis,
fecal bile acids,
diagnosis,
elevated coefficient of variation,
research
The role of intestinal epithelial barrier function in the development of NEC.
2015
intestinal epithelium,
nec,
barrier function,
intestinal health,
development
Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis
2014
t lymphocytes,
intestinal health,
necrotizing enterocolitis,
premature infants,
immune response
Discrimination of GutCheck(NEC) a clinical risk index for necrotizing enterocolitis.
2014
gut health,
medical diagnosis,
clinical risk assessment,
necrotizing enterocolitis,
discrimination
