Profile

David Labiner

Member of the Graduate Faculty | Professor, Neurology | Department Head, Neurology | Professor, Neurosurgery | Professor, Pharmacy Practice-Science

Neurology

Full Page

Overview

Research

Collaboration(40)

Page 1 of 8

Grants(39)

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures
Active·2024·$1.8M / $440.6K·
External
Principal Investigator (PI)
epilepsy, medication, clinical trial, adjunctive therapy, safety
A Phase 2, multicenter, Open-Label, Long-Term Safety Study of LP352 in Subjects with Developmental and Epileptic Encephalopathy who Completed Study LP352-201 and are Candidates for Continuous Treatmen
Active·2024·$79.1K / $19.8K·
External
Principal Investigator (PI)
epileptic encephalopathy, long-term safety, developmental disorders, continuous treatment
A First-in-human (FIH) Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)
Active·2023·$749.8K·
External
Principal Investigator (PI)
neuroscience, epilepsy, clinical trial, drug resistance, inhibitory interneurons
A Phase 1b/2a Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy
Active·2023·$1.6M / $543.6K·
External
Principal Investigator (PI)
clinical trials, pharmacology, safety, efficacy, dose escalation
SIP 19-003: Managing Epilepsy Well 2.0 (MEW) Network - Collaborating Center
Active·2019·$771.3K / $1.5M·
External
Principal Investigator (PI)
health promotion, disease prevention, research centers, public health

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Publications(43)

Recent

Accreditation of Epilepsy Centers.

2021

medical, neurology, accreditation, healthcare, epilepsy

Healthcare resource utilization and costs before and after lacosamide initiation as adjunctive therapy among patients with epilepsy in the United States

2019

epilepsy, healthcare costs, lacosamide, healthcare utilization, adjunctive therapy

Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency

2019

neuronal excitability, temporal lobe epilepsy, signaling pathways, hippocampal tissue, seizure frequency

An update on the prevalence and incidence of epilepsy among older adults

2018

epilepsy, older adults, prevalence, incidence, update

Cost sharing for antiepileptic drugs: medication utilization and health plan costs

2018

pharmacoeconomics, healthcare costs, medication adherence, epilepsy treatment, health insurance

Indications and methodology for video-electroencephalographic studies in the epilepsy monitoring unit

2018

epilepsy, electroencephalographic, video, monitoring unit, methodology

Leukocyte expression profiles reveal gene sets with prognostic value for seizure-free outcome following stereotactic laser amygdalohippocampotomy

2018

gene expression, prognostic markers, seizure outcome, laser amygdalohippocampotomy, leukocyte profiles

Economic impact of epilepsy and the cost of nonadherence to antiepileptic drugs in older Medicare beneficiaries

2018

epilepsy, healthcare cost, medicare, adherence, economic impact

Psychosocial Impact of Epilepsy in Older Adults

2016

epilepsy, psychosocial impact, older adults, mental health, quality of life

Felt and enacted stigma in elderly persons with epilepsy: A qualitative approach

2016

epilepsy, stigma, elderly, qualitative research, psychosocial impact

People

Profile

David Labiner

Collaboration(40)

Mindy Fain

H-H. Sherry Chow

Denise Roe

Bonnie LaFleur

Cecilia Rosales

Grants(39)

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

A Phase 2, multicenter, Open-Label, Long-Term Safety Study of LP352 in Subjects with Developmental and Epileptic Encephalopathy who Completed Study LP352-201 and are Candidates for Continuous Treatmen

A First-in-human (FIH) Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)

A Phase 1b/2a Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy

SIP 19-003: Managing Epilepsy Well 2.0 (MEW) Network - Collaborating Center

Publications(43)

Accreditation of Epilepsy Centers.

Healthcare resource utilization and costs before and after lacosamide initiation as adjunctive therapy among patients with epilepsy in the United States

Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency

An update on the prevalence and incidence of epilepsy among older adults

Cost sharing for antiepileptic drugs: medication utilization and health plan costs

Indications and methodology for video-electroencephalographic studies in the epilepsy monitoring unit

Leukocyte expression profiles reveal gene sets with prognostic value for seizure-free outcome following stereotactic laser amygdalohippocampotomy

Economic impact of epilepsy and the cost of nonadherence to antiepileptic drugs in older Medicare beneficiaries

Psychosocial Impact of Epilepsy in Older Adults

Felt and enacted stigma in elderly persons with epilepsy: A qualitative approach