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Profile
Yin Chen
Professor, BIO5 Institute | Member of the Graduate Faculty | Professor, Pharmacology and Toxicology
Pharmacology and Toxicology
Overview
Research
More
Collaboration
(42)
Bernard Futscher
Mutual work: 1 Proposal
Collaboration Details
Dean Billheimer
Mutual work: 2 Proposals
Collaboration Details
Haiquan Li
Mutual work: 1 Proposal
Collaboration Details
Chengcheng Hu
Mutual work: 1 Proposal
Collaboration Details
Nathan Ellis
Mutual work: 1 Publication
Collaboration Details
Page 1 of 9
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Grants
(13)
Fungal Asthma and Lung Innate Immunity
Active
·
2020
·
$1.4M / $2.1M
·
External
Principal Investigator (PI)
fungal infections,
asthma,
lung immunology,
innate immunity,
respiratory diseases
Environmental Health Sciences: Transformational Research Undergraduate Experience (E-H-TRUE)
Active
·
2020
·
$432K
·
External
Principal Investigator (PI)
environmental health,
transformational research,
undergraduate experience,
e-h-true,
science education
Vanadium, Calcineurin, and Pulmonary Health
2018
·
$217K / $434K
·
External
Principal Investigator (PI)
pulmonary health,
vanadium toxicity,
calcineurin inhibition,
respiratory diseases,
cell signaling
Mechanisms of Epithelium-Directed Change of Permissiveness for Rhinoviral Infection
2018
·
$401K / $422.1K
·
External
Principal Investigator (PI)
viral infection,
epithelial cells,
immunology,
respiratory diseases,
molecular biology
Arsenic exposure, CC16 and its Effect on Pulmonary Function
2017
·
$820.3K / $1.7M
·
External
Multiple Principal Investigator (MPI)
arsenic exposure,
pulmonary function,
cc16,
toxicology,
respiratory health
Page 1 of 3
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Publications
(57)
Recent
Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes
2023
asthma,
atopic status,
age of onset,
asthma subphenotypes,
comorbidity
A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases
2023
fluorescence polarization,
high-throughput screening,
sam-binding sites,
sars-cov-2,
viral methyltransferases
The main protease of SARS-CoV-2 downregulates innate immunity via a translational repression
2023
sars-cov-2,
innate immunity,
protease,
translational repression,
viral immune evasion
AG1478 Elicits a Novel Anti-Influenza Function via an EGFR-Independent, GBF1-Dependent Pathway
2022
influenza,
egfr,
antiviral,
cell signaling,
drug development
Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model
2022
macrophage subtypes,
sars-cov-2 infection,
human pluripotent stem cell-derived model,
differential effects,
immunology
NISC: Neural Network-Imputation for Single-Cell RNA Sequencing and Cell Type Clustering
2022
single-cell rna sequencing,
neural network,
imputation,
cell type clustering,
genomics
Protective function of interleukin-22 in pulmonary fibrosis
2021
interleukin-22,
pulmonary fibrosis,
protective function,
immune response,
lung injury
Novel Mouse Models of Fungal Asthma
2021
mouse models,
fungal asthma,
novel models,
fungal infections,
respiratory diseases
DeepBiome: a phylogenetic tree informed deeneural network for microbiome data analysis NPJSBA-00578-T)
2021
microbiome,
phylogenetic analysis,
neural network,
data analysis,
phylogenetic tree
Lung developmental is altered after inhalation exposure to various concentrations of calcium arsenate
2021
lung development,
inhalation exposure,
calcium arsenate,
developmental toxicity,
inhaled toxins