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Steven Schwartz

Professor, BIO5 Institute | Member of the Graduate Faculty | Regents Professor | Professor, Chemistry and Biochemistry-Sci | Professor, Applied Mathematics - GIDP

Chemistry & Biochemistry - Sci
Map Page
10+ Collaborators
$12.5M / $24.4M Funding
20+ Grants
120+ Publications
6+ Courses

Research Area

enzyme kinetics, protein dynamics, biochemistry, enzyme catalysis, protein structure, molecular dynamics, molecular biology, catalysis, enzyme mechanism, isotope effects, structural biology, enzyme design, biophysics, evolution, biophysical chemistry, enzyme engineering, directed evolution, cardiomyopathy, genetic cardiomyopathy

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    Recent

    Investigation of the Recovery Stroke and ATP Hydrolysis and Changes Caused Due to the Cardiomyopathic Point Mutations in Human Cardiac β Myosin

    2021
    cardiomyopathy, atp hydrolysis, stroke, point mutations, human cardiac β myosin

    Computational and biophysical determination of pathogenicity of variants of unknown significance in cardiac thin filament

    2021
    genetic variants, cardiac health, biophysical modeling, pathogenicity, computational analysis

    A Proposed Mechanism for the Initial Myosin Binding Event on the Cardiac Thin Filament: A Metadynamics Study

    2021
    cardiac muscle, molecular dynamics, myosin binding, muscle contraction, biophysical interactions

    Inverse heavy enzyme isotope effects in methylthioadenosine nucleosidases

    2021
    enzyme kinetics, isotope effects, nucleosidases, biochemistry, catalysis

    Directed Evolution's Influence on Rapid Density Fluctuations Illustrates How Protein Dynamics Can Become Coupled to Chemistry

    2020
    directed evolution, protein dynamics, chemistry, rapid density fluctuations, influence

    Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

    2020
    cardiomyopathy, cardiac, twitch, modulation, murine

    Multiple Reaction Pathways in the Morphinone Reductase-Catalyzed Hydride Transfer Reaction

    2020
    enzyme catalysis, organic chemistry, reaction mechanism, biocatalysis, enzyme kinetics

    Mechanochemical Function of Myosin II: Investigation into the Recovery Stroke and ATP Hydrolysis

    2020
    biomechanics, molecular biology, biochemistry, muscle physiology, enzyme kinetics

    Role of Protein Motions in Catalysis by Formate Dehydrogenase

    2020
    enzyme catalysis, protein dynamics, biochemistry, enzyme mechanism, protein function

    A Classical Molecular Dynamics Simulation Study of Interfacial and Bulk Solution Aggregation Properties of Dirhamnolipids

    2020
    molecular dynamics, interfacial aggregation, solution properties, bulk solution, dirhamnolipids

    • Walter Klimecki

    • Hendrikus Granzier

    • Robin Polt

    • Raina Maier

    • Craig Aspinwall

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    • Graduate Research Assistant

      Grant: 020074-00001

      I am looking for talented graduate students for this project.

    • Graduate Research Assistant

      Grant: 020361-00001

      I am always looking for talented graduate students.

    • Mathematical Methods for Chemists

    • Majors General Chemistry II

    • Physical Chemistry

    • Quantum Chemistry

    • General Chemistry Lecture II: Quantitative Approach

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    Steven Schwartz | KMap Profile - Institutional Knowledge Map (KMap)