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Dimitris Antoniou
Associate Research Professor | Member of the Graduate Faculty
Chemistry & Biochemistry - Sci
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Research Area
protein dynamics,
enzyme kinetics,
enzyme catalysis,
biochemical kinetics,
protein structure,
transition path sampling,
isotope effects,
catalysis,
biochemistry,
hydride transfer
Publications
(50)
Recent
The Evolution of the Acylation Mechanism in β-Lactamase and Rapid Protein Dynamics
2024
enzyme mechanism,
protein dynamics,
evolutionary biology,
enzyme catalysis,
protein structure
Atomistic description of the relationshibetween protein dynamics and catalysis with transition path sampling
2023
protein dynamics,
catalysis,
transition path sampling,
atomistic description,
relationshibetween
Connecting conformational motions to rapid dynamics in human purine nucleoside phosphorylase
2022
protein dynamics,
enzyme kinetics,
molecular biophysics,
biochemical kinetics,
structural biology
Method for Identifying Common Features in Reactive Trajectories of a Transition Path Sampling Ensemble
2022
reactive trajectories,
transition path sampling,
common features,
identifying method,
ensemble
Inverse heavy enzyme isotope effects in methylthioadenosine nucleosidases
2021
enzyme kinetics,
isotope effects,
nucleosidases,
biochemistry,
catalysis
Linking Protein Dynamics to Enzyme Catalysis
2020
protein dynamics,
enzyme catalysis,
biochemistry,
molecular biology,
biophysics
Role of protein motions in catalysis by formate dehydrogenase
2020
protein dynamics,
enzyme catalysis,
formate dehydrogenase,
protein structure
Optimization of the turnover in artificial enzymes via directed evolution results in the coupling of protein dynamics to chemistry
2019
enzyme engineering,
directed evolution,
protein dynamics,
artificial enzymes,
optimization
Inverse enzyme isotope effects in human purine nucleoside phosphorylase with heavy asparagine labels
2018
enzyme kinetics,
isotope labeling,
nucleoside metabolism,
enzyme catalysis,
biochemical kinetics
Incorporating Fast Protein Dynamics into Enzyme Design: A Proposed Mutant Aromatic Amine Dehydrogenase
2017
protein dynamics,
enzyme design,
mutant,
aromatic amine,
dehydrogenase
Collaborations
(2)
Steven Schwartz
Mutual work: 1 Proposal
Collaboration Details
Jil Tardiff
Mutual work: 1 Proposal
Collaboration Details
50+ Publications
