Immunodeficiency refers to a weakened or compromised immune system, which can lead to an increased susceptibility to infections and other health complications. There are various types of immunodeficiencies, including primary immunodeficiency disorders which are inherited, and secondary immunodeficiency disorders which can be acquired due to factors such as medications, infections, or certain medical conditions. Research in the field of immunodeficiency focuses on understanding the underlying causes of these disorders, developing novel treatments and therapies to enhance immune function, and improving diagnosis and management of immunodeficiency conditions. This research is crucial in improving the quality of life and outcomes for individuals with compromised immune systems.