Hemeoxygenase-1 (HO-1) is an enzyme that plays a critical role in the breakdown of heme, a component of hemoglobin, into biliverdin, carbon monoxide, and iron. This breakdown process is essential for maintaining cellular homeostasis and protecting cells from oxidative stress. Research on HO-1 has focused on its role in various diseases such as cancer, cardiovascular diseases, and inflammatory conditions. Studies have also shown that HO-1 has anti-inflammatory, antioxidant, and cytoprotective properties, making it a potential target for therapeutic interventions. Overall, research on hemeoxygenase-1 aims to better understand its physiological functions and develop strategies to harness its therapeutic potential in various diseases.