Enhancers are short, non-coding DNA sequences that play a crucial role in regulating gene expression. They work by binding to specific proteins called transcription factors, which in turn help activate or enhance the transcription of nearby genes. Enhancers can be located far away from the gene they regulate and can work in a tissue-specific or developmental stage-specific manner. Overall, enhancers are important for controlling when and where genes are expressed, and their dysregulation can lead to various diseases and disorders.