Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease that makes it difficult to breathe. This condition is commonly caused by smoking, but other factors such as air pollution and genetics may also play a role. Research in COPD focuses on understanding the underlying causes of the disease, developing better diagnostic tools, improving treatment options, and finding ways to prevent or slow down its progression. This includes studying how inflammation and oxidative stress contribute to COPD, evaluating new medications and therapies, and exploring the potential benefits of pulmonary rehabilitation and lung transplantation for patients with severe cases. Overall, research in COPD aims to improve the quality of life for patients, reduce exacerbations and hospitalizations, and ultimately find a cure for this debilitating condition.