Cyclin-dependent kinase 5 (CDK5) is a protein kinase that plays a crucial role in various cellular processes, including neuronal development, synaptic plasticity, and cell cycle regulation. Research in the area of CDK5 focuses on understanding its functions in normal physiological processes as well as its involvement in various diseases, particularly neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. Studies have shown that dysregulation of CDK5 activity can lead to abnormal neuronal development, synaptic dysfunction, and cell death, which may contribute to the pathogenesis of neurodegenerative diseases. Therefore, researchers are investigating potential therapeutic strategies targeting CDK5 to treat these conditions. Overall, research in the area of CDK5 aims to further elucidate its molecular mechanisms and identify potential targets for drug development to modulate its activity in various disease states.