Bixin is a natural red-orange pigment found in annatto seeds, which are derived from the annatto tree (Bixa orellana). It is a carotenoid compound that has been studied for its antioxidant, anti-inflammatory, and potentially anti-cancer properties. Bixin has been used traditionally in indigenous medicine and as a food coloring agent. Research on bixin has focused on its potential health benefits, including its effects on oxidative stress, inflammation, and cancer prevention. Studies have also investigated its potential as a natural food preservative and its role in improving skin health. Overall, research on bixin suggests that it may have potential therapeutic applications in various health conditions.