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Suchithranga Perera

Instructor, Chemistry and Biochemistry-Sci,

Chemistry & Biochemistry - Sci
suchi@arizona.edu

520/621-3607

Suchithranga Perera experts in biophysics, molecular biology, g protein-coupled receptors, biochemistry, gpcrs, cell biology, nmr spectroscopy, rhodopsin, biostatistics, neutron scattering, structural biology, stroke, biomaterials, tissue engineering, mass spectrometry, membrane proteins, epidemiology, immunology, rehabilitation, psychiatry, drug delivery, x-ray crystallography, computational biology, bioinformatics, infectious disease epidemiology, x-ray scattering, dna repair, pharmacoepidemiology, otolaryngology, virology, health services research, health policy, bibliometrics, information science, scholarly communication, physiotherapy, clinical trials, traumatic brain injury, gynecologic pathology, molecular imaging, rheumatology, membranes, lipids, odontologia, infectious diseases, bioengineering, molecular dynamics simulation, rhodops, biomedical engineering, ultrasound imaging, soft matter, proteomics, ultrafast spectroscopy, femtosecond laser, membrane trafficking, neurosurgery

Courses

Chemical Thinking I

General Chemistry II

Chemical Thinking II

General Chemistry I

Technologies / Patents

	2021	Composition Comprising a Lyophilized Detergent-Solubilized Protein
	2020	Powdered G-Protein Coupled Receptors (GPCR)
	1899	Powdered G-Protein Coupled Receptors (GPCR)

Publications (86)

Recent

2023	Hybrid‐Mobile Stroke Unit: Opening the Indication Spectrum for Stroke Mimics and Beyond
2022	How osmotic stress and crowding affect G-protein-coupled receptor activation
2022	Hydration-mediated G-protein–coupled receptor activation
2022	Activation of G-protein-coupled receptors by hydration driven sponge mechanism
2022	Hydration-water and membrane lipids modulate G-protein-coupled receptor activation
2022	Time-resolved functional expansion of visual rhodopsin detected by x-ray scattering
2022	Extent of Internal Hydration influence the Activation of GPCR Rhodopsin.
2022	Modulation of GPCR Rhodopsin Function by Membrane Lipids and Water.
2022	Functional dynamics of G-protein-coupled receptor shown by femtosecond X-ray scattering
2021	Membrane lipids and cellular water modulate G-protein-coupled receptor rhodopsin activation
2021	Native mass spectrometry reveals the simultaneous binding of lipids and zinc to rhodopsin
2021	Functional Expansion of G-Protein-Coupled Receptor Shown by Time-Resolved X-Ray Scattering
2021	Hydration Drives Activation of the G‐Protein‐Coupled Receptor Rhodopsin
2021	Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser
2021	Effects of Soft Matter on G-Protein-Coupled Receptor Activation
2021	Lipid Membrane and Protein Hydration Level Play a Critical Role in GPCR Activation
2021	Hydration and Protonation Effects on Activation of G-Protein-Coupled Receptors
2021	Composition comprising a lyophilized detergent-solubilized protein
2021	Solvation Drives G-Protein-Coupled Receptor Activation
2021	Activation of the G‐protein‐coupled receptor rhodopsin by water
2021	Membrane Lipids and Cellular Water Modulate the G‐Protein–Coupled Receptor Activation
2020	Association between multivitamin supplementation and mortality among patients with Ebola virus disease: an international multisite cohort study
2020	Active Rhodopsin Chromophore Conformation Revealed by Solid-state 2H NMR and QM/MM Simulations
2020	Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser
2020	Allosteric regulation of GPCR Rhodopsin by soft matter
2020	G-protein-coupled receptors are solvent-swollen in the functionally active state
2020	Association between treatment with oral third‐generation cephalosporin antibiotics and mortality outcomes in Ebola virus disease: a multinational retrospective cohort study
2020	Water and Membrane Lipids Govern G-Protein Activation
2020	Detergent-protein composition comprising lyophilized detergent-solubilized protein
2020	Modulation of GPCR Function by Membrane Lipids and Water
2020	Rhodopsin Activation in Lipid Membranes Based on Solid-State NMR Spectroscopy
2020	Global Research Highlights
2020	Soft Matter Control of GPCR Function by Membrane Lipids and Water
2020	Rhodopsin's Ultra-Fast Activation Dynamics in Bilayer and Micelle Environments
2019	Study of Ultra-Fast Rhodopsin Activation Dynamics with Molecular Dynamics Simulations
2019	Retinal Flipping During Rhodopsin Activation Revealed by Solid State 2H NMR and QM/MM Simulations
2019	Quasielastic and elastic neutron scattering of membrane proteins
2019	Flexible surface model for lipid-protein interactions
2019	G-protein-coupled receptor activation mediated by internal hydration
2019	Association Between Vitamin A Supplementation and Mortality Among Patients with Ebola Virus Disease: An International Multisite Cohort Study
2019	Hydration Modulates G‐Protein‐Coupled Receptor Signaling
2019	Functional Water Dynamics in Rhodopsin Using Solid‐State Deuterium NMR Spectroscopy
2019	Sponge Model of G-Protein Binding and Unbinding in Membranes
2019	Structural Fluctuations in Rhodopsin Activation Revealed by Neutron Scattering
2019	Impact of change in head and neck position on ultrasound localisation of the cricothyroid membrane: an observational study
2018	Small-angle neutron scattering reveals energy landscape for rhodopsin photoactivation
2018	Powdered g-protein coupled receptors (gpcr)
2018	Investigation of Photoinduced Oligomerization of Rhodopsin by Native Mass Spectrometry
2018	EFFECT OF MASS ARTESUNATE-AMODIOQUINE DISTRIBUTION ON EBOLA-RELATED MORTALITY IN SIERRA LEONE
2018	G-Protein-Coupled Receptor Activation through Membrane Deformation
2018	314 Treatment With Intravenous Fluid Therapy Was Not Associated With Improved Survival Among Patients With Ebola Virus Disease: An International Multisite Cohort Study
2018	Hydration Thermodynamics of a Powdered G-Protein-Coupled Receptor
2018	EARLY INTRAVENOUS FLUID THERAPY AND MORTALITY OUTCOMES AMONG PATIENTS WITH EBOLA VIRUS DISEASE: A MULTISITE RETROSPECTIVE PROPENSITY-MATCHED COHORT STUDY
2017	Role of Soft Matter in G-Protein-Coupled Receptor Signaling
2017	Energy Landscape Model and Spatial Motion Models in Rhodopsin Activation
2017	Membrane Lipid-Protein Interactions
2017	Multiscale GPCR Activation in Lipid Membranes Probed by Solid-State NMR and Scattering Methods
2017	Solid-state deuterium NMR spectroscopy of rhodopsin
2017	Time-Resolved Wide-Angle X-Ray Scattering Reveals Protein Quake in Rhodopsin Activation
2016	Quasi-elastic neutron scattering reveals ligand-induced protein dynamics of a G-protein-coupled receptor
2016	Powdered G-protein-coupled receptors
2016	Neutron Scattering Reveals Protein Fluctuations in GPCR Activation
2016	A Usual G‐Protein‐Coupled Receptor in Unusual Membranes
2016	Hydration mediated G-protein-coupled receptor activation
2016	Computational and Experimental Studies of Lipid-Protein Interactions in Biomemrane Function
2015	Rhodopsin Photoactivation Dynamics Revealed by Quasi-Elastic Neutron Scattering
2015	Investigation of rhodopsin dynamics in its signaling state by solid-state deuterium NMR spectroscopy
2015	Increased prevalence of diabetes in schizophrenia but improved glucose, blood pressure and lipid profile and lower microvascular complications in patients prescribed …
2015	RHODOPSIN: METHODS AND PROTOCOLS
2015	Small Angle Neutron and X-Ray Scattering Reveal Conformational Differences in Detergents Affecting Rhodopsin Activation
2015	Spontaneous Reconstitution of Bovine Rhodopsin into Artificial Membranes
2014	Role of Membrane Lipids in Activating G-Protein-Coupled Receptors
2014	Ensemble Activation of G-Protein-Coupled Receptors Revealed by Small-Angle Neutron Scattering
2014	G-Protein-Coupled Receptor Activation Investigated using Small-Angle Neutron Scattering
2014	Lipid-Mediated Activation of G-Protein-Coupled Receptors in Membranes
2013	Increasing patients' activity, participation and social interaction on an acute stroke unit
2013	Gestational diabetes can be safely and effectively managed with risk-stratified community and hospital based care in a high prevalence population
2013	Diabetes and schizophrenia: exploring the associations: determining the extent of diabetes and the quality of diabetes care within a clozapine (schizophrenia) clinic in Edinburgh
2013	Does the evidence supporting a correlation between intensity of therapy practice and better outcomes apply in the clinical setting of a hyper-acute and acute stroke unit?
2013	Membrane Bilayer Environment Influences Thermodynamics of Rhodopsin Membrane Protein-Lipid Interactions
2012	An observational study of intrathecal injection
2012	Assessing physiotherapy interventions on an acute stroke unit against national clinical guidelines: developing an audit tool to evaluate and improve a physiotherapy service
2011	A Bibliometric Study on WHO Publications Available in the Peradeniya Medical Library
2011	Routine HIV screening in elective and emergency surgical patients-doctors' and patients' perspectives
1996	Growth of Epstein-Barr virus-associated B-lymphoproliferative disease tissue in a severe combined immunodeficient mouse
1988	An additional tactile test: further developments in tactile tests to confirm laryngeal placement of tracheal tubes

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