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  • CTI
    Chemical Thinking II

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    Chemical Thinking I

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    General Chemistry I

  • GCI
    General Chemistry II

Technologies / Patents
      Publications (88)
      Recent
      • Water is a powerful dynamic allosteric modulator in rhodopsin activation

        2023

      • X-ray scattering exhibits time-resolved view of rhodopsin activation

        2023

      • Femtosecond dynamics of rhodopsin revealed by X-ray laser

        2023

      • Electronic structure calculations and deuterium NMR spectroscopy reveal retinal mobility in rhodopsin activation

        2023

      • Hybrid‐Mobile Stroke Unit: Opening the Indication Spectrum for Stroke Mimics and Beyond

        2023

      • Activation of G-protein-coupled receptors by hydration driven sponge mechanism

        2022

      • How osmotic stress and crowding affect G-protein-coupled receptor activation

        2022

      • Time-resolved functional expansion of visual rhodopsin detected by x-ray scattering

        2022

      • Hydration-mediated G-protein–coupled receptor activation

        2022

      • Functional dynamics of G-protein-coupled receptor shown by femtosecond X-ray scattering

        2022

      • Extent of Internal Hydration influence the Activation of GPCR Rhodopsin.

        2022

      • Hydration-water and membrane lipids modulate G-protein-coupled receptor activation

        2022

      • Modulation of GPCR Rhodopsin Function by Membrane Lipids and Water.

        2022

      • Solvation Drives G-Protein-Coupled Receptor Activation

        2021

      • Effects of Soft Matter on G-Protein-Coupled Receptor Activation

        2021

      • Hydration and Protonation Effects on Activation of G-Protein-Coupled Receptors

        2021

      • Membrane Lipids and Cellular Water Modulate the G‐Protein–Coupled Receptor Activation

        2021

      • Composition comprising a lyophilized detergent-solubilized protein

        2021

      • Native mass spectrometry reveals the simultaneous binding of lipids and zinc to rhodopsin

        2021

      • Lipid Membrane and Protein Hydration Level Play a Critical Role in GPCR Activation

        2021

      • Functional Expansion of G-Protein-Coupled Receptor Shown by Time-Resolved X-Ray Scattering

        2021

      • Activation of the G‐protein‐coupled receptor rhodopsin by water

        2021

      • Hydration Drives Activation of the G‐Protein‐Coupled Receptor Rhodopsin

        2021

      • Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser

        2021

      • Detergent-protein composition comprising lyophilized detergent-solubilized protein

        2020

      • Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser

        2020

      • Association between treatment with oral third‐generation cephalosporin antibiotics and mortality outcomes in Ebola virus disease: a multinational retrospective cohort study

        2020

      • Global Research Highlights

        2020

      • G-protein-coupled receptors are solvent-swollen in the functionally active state

        2020

      • Active Rhodopsin Chromophore Conformation Revealed by Solid-state 2H NMR and QM/MM Simulations

        2020

      • Allosteric regulation of GPCR Rhodopsin by soft matter

        2020

      • Rhodopsin's Ultra-Fast Activation Dynamics in Bilayer and Micelle Environments

        2020

      • Association between multivitamin supplementation and mortality among patients with Ebola virus disease: an international multisite cohort study

        2020

      • Rhodopsin Activation in Lipid Membranes Based on Solid-State NMR Spectroscopy

        2020

      • Water and Membrane Lipids Govern G-Protein Activation

        2020

      • Modulation of GPCR Function by Membrane Lipids and Water

        2020

      • G-protein-coupled receptor activation mediated by internal hydration

        2019

      • Hydration Modulates G‐Protein‐Coupled Receptor Signaling

        2019

      • Sponge Model of G-Protein Binding and Unbinding in Membranes

        2019

      • Flexible surface model for lipid-protein interactions

        2019

      • Retinal Flipping During Rhodopsin Activation Revealed by Solid State 2H NMR and QM/MM Simulations

        2019

      • Functional Water Dynamics in Rhodopsin Using Solid‐State Deuterium NMR Spectroscopy

        2019

      • Study of Ultra-Fast Rhodopsin Activation Dynamics with Molecular Dynamics Simulations

        2019

      • Structural Fluctuations in Rhodopsin Activation Revealed by Neutron Scattering

        2019

      • Association Between Vitamin A Supplementation and Mortality Among Patients with Ebola Virus Disease: An International Multisite Cohort Study

        2019

      • Impact of change in head and neck position on ultrasound localisation of the cricothyroid membrane: an observational study

        2019

      • Quasielastic and elastic neutron scattering of membrane proteins

        2019

      • EARLY INTRAVENOUS FLUID THERAPY AND MORTALITY OUTCOMES AMONG PATIENTS WITH EBOLA VIRUS DISEASE: A MULTISITE RETROSPECTIVE PROPENSITY-MATCHED COHORT STUDY

        2018

      • Investigation of Photoinduced Oligomerization of Rhodopsin by Native Mass Spectrometry

        2018

      • Small-angle neutron scattering reveals energy landscape for rhodopsin photoactivation

        2018

      • 314 Treatment With Intravenous Fluid Therapy Was Not Associated With Improved Survival Among Patients With Ebola Virus Disease: An International Multisite Cohort Study

        2018

      • Powdered g-protein coupled receptors gpcr)

        2018

      • Hydration Thermodynamics of a Powdered G-Protein-Coupled Receptor

        2018

      • G-Protein-Coupled Receptor Activation through Membrane Deformation

        2018

      • Solid-state deuterium NMR spectroscopy of rhodopsin

        2017

      • Membrane Lipid-Protein Interactions

        2017

      • Energy Landscape Model and Spatial Motion Models in Rhodopsin Activation

        2017

      • Multiscale GPCR Activation in Lipid Membranes Probed by Solid-State NMR and Scattering Methods

        2017

      • Role of Soft Matter in G-Protein-Coupled Receptor Signaling

        2017

      • Time-Resolved Wide-Angle X-Ray Scattering Reveals Protein Quake in Rhodopsin Activation

        2017

      • Neutron Scattering Reveals Protein Fluctuations in GPCR Activation

        2016

      • A Usual G‐Protein‐Coupled Receptor in Unusual Membranes

        2016

      • Powdered G-protein-coupled receptors

        2016

      • Computational and Experimental Studies of Lipid-Protein Interactions in Biomemrane Function

        2016

      • Hydration mediated G-protein-coupled receptor activation

        2016

      • Quasi-elastic neutron scattering reveals ligand-induced protein dynamics of a G-protein-coupled receptor

        2016

      • Rhodopsin Photoactivation Dynamics Revealed by Quasi-Elastic Neutron Scattering

        2015

      • Small Angle Neutron and X-Ray Scattering Reveal Conformational Differences in Detergents Affecting Rhodopsin Activation

        2015

      • Spontaneous Reconstitution of Bovine Rhodopsin into Artificial Membranes

        2015

      • Increased prevalence of diabetes in schizophrenia but improved glucose, blood pressure and lipid profile and lower microvascular complications in patients prescribed …

        2015

      • RHODOPSIN: METHODS AND PROTOCOLS

        2015

      • Investigation of rhodopsin dynamics in its signaling state by solid-state deuterium NMR spectroscopy

        2015

      • Ensemble Activation of G-Protein-Coupled Receptors Revealed by Small-Angle Neutron Scattering

        2014

      • Role of membrane lipids in activating G-protein-coupled receptors

        2014

      • G-Protein-Coupled Receptor Activation Investigated using Small-Angle Neutron Scattering

        2014

      • Lipid-Mediated Activation of G-Protein-Coupled Receptors in Membranes

        2014

      • Gestational diabetes can be safely and effectively managed with risk-stratified community and hospital based care in a high prevalence population

        2013

      • Increasing patients' activity, participation and social interaction on an acute stroke unit

        2013

      • Membrane Bilayer Environment Influences Thermodynamics of Rhodopsin Membrane Protein-Lipid Interactions

        2013

      • Diabetes and schizophrenia: exploring the associations: determining the extent of diabetes and the quality of diabetes care within a clozapine schizophrenia) clinic in Edinburgh

        2013

      • Does the evidence supporting a correlation between intensity of therapy practice and better outcomes apply in the clinical setting of a hyper-acute and acute stroke unit?

        2013

      • An observational study of intrathecal injection

        2012

      • Assessing physiotherapy interventions on an acute stroke unit against national clinical guidelines: developing an audit tool to evaluate and improve a physiotherapy service

        2012

      • A Bibliometric Study on WHO Publications Available in the Peradeniya Medical Library

        2011

      • Routine HIV screening in elective and emergency surgical patients-doctors' and patients' perspectives

        2011

      • Growth of Epstein-Barr virus-associated B-lymphoproliferative disease tissue in a severe combined immunodeficient mouse

        1996

      • An additional tactile test: further developments in tactile tests to confirm laryngeal placement of tracheal tubes

        1988

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