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Picture of Ronald Lynch

Ronald Lynch

Professor, BIO5 Institute | Professor, Biomedical Engineering | Professor, Physiology | Member of the Graduate Faculty | Professor, Physiological Sciences - GIDP | Director, Aribi Institute | Associate Professor, Pharmacology | Associate Director, Shared Resources

Collaboration(32)

H-H. Sherry Chow
Cynthia Thomson
Denise Roe
Andrew Rouse
David Besselsen

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Grants(25)

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Publications(32)

Recent

Lower oxygen consumption and Complex I activity in mitochondria isolated from skeletal muscle of fetal sheewith intrauterine growth restriction

2020

mitochondrial function, intrauterine growth restriction, skeletal muscle, oxygen consumption, complex i activity

Oxygen Perfusion Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling

2019

islet function, oxygen perfusion, pancreas preservation, insulin secretion, proinflammatory signaling

Multivalent activation of GLP-1 and Sulfonylurea receptors modulates β-cell Second Messenger Signaling and Insulin Secretion

2019

glp-1 receptor, sulfonylurea receptor, β-cell signaling, insulin secretion, second messenger signaling

Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices

2019

epithelial barriers, microfluidic devices, endothelial barriers, permeability, transwells

Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells

2018

adrenergic receptor stimulation, oxidative metabolism, rat islets, min6 cells, cellular metabolism

In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β-cell function, and transcriptomes

2018

islet oxygen demand, β-cell function, transcriptomes, porcine islet, juvenile neonatal islet

Comment on Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism

2017

g-protein-coupled receptor, pharmacologic tools, x-linked ocular albinism, novel ligands, investigating

Islet adaptations in fetal sheepersist following chronic exposure to high norepinephrine

2017

islet adaptations, fetal development, norepinephrine effects, endocrine regulation, metabolic programming

Acute Ischemia Induced by High-Density Culture Increases Cytokine Expression and Diminishes the Function and Viability of Highly Purified Human Islets of Langerhans

2017

ischemic injury, cytokine expression, islet viability, cell culture, function impairment

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302

2015

pancreatic cancer, hypoxia, prodrug, pyruvate, tumor sensitization