Profile

Richard Simpson

Nutritional Sci Wellness - RES

Full Page

Overview

Research

Collaboration(23)

Page 1 of 5

Grants(20)

Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training Program
Active·2024·$0 / $292.3K·
External
aging, infection, inflammation, pre-doctoral, training
Exercise as an Immune Adjuvant for Gamma Delta T-cell Therapies in Hematologic Malignancies
Active·2023·$553.5K / $1.2M·
External
Principal Investigator (PI)
exercise, immune adjuvant, gamma delta t-cell, hematologic malignancies
Use of Humanized NSG mice to optimally balance GvHD and GvL against hematologic malignancies
Active·2023·$200K / $400K·
External
Co-Investigator (COI)
immunotherapy, cancer, mouse models, hematologic malignancies, gvhd
Role for Myeloid Acid Ceramidase in Colon Inflammation and Cancer
Active·2022·$49.1K / $983K·
External
Co-Investigator (COI)
colon cancer, inflammation, myeloid cells, ceramidase, role in cancer development
Validation of Multisystem Countermeasures Protocol for Spaceflight during Antartica Winterover at Palmer Station
Active·2022·$155K·
External
Principal Investigator (PI)
spaceflight, countermeasures, antarctica, validation, multisystem

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Publications(253)

Recent

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

2024

covid-19, vaccination, t cells, sars-cov-2, exercise

Relationships between T-lymphocytes and physical function in adults with chronic lymphocytic leukemia: Results from the HEALTH4CLL pilot study

2023

t lymphocytes, physical function, chronic lymphocytic leukemia, adults

Multiagent Intratumoral Immunotherapy Can Be Effective in A20 Lymphoma Clearance and Generation of Systemic T Cell Immunity

2023

immunotherapy, cancer, tumor microenvironment, t-cell immunity, multiagent therapy

Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice

2023

lymphocytes, exercise, anti-tumor profile, graft-versus-leukemia, transcriptomic

The effect of physical exercise on anticancer immunity

2023

exercise, anticancer, immunity

Clonal kinetics and single-cell transcriptional profiles of T-cells mobilized to blood by acute exercise

2023

immunology, exercise physiology, cellular biology, transcriptomics, hematology

Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2

2023

exercise, immune response, sars-cov-2, antigen-specific t-cells, neutralizing antibodies

Comparable Efficacy of Oral Bendamustine versus Intravenous Administration in Treating Hematologic Malignancies

2023

drug administration, hematologic malignancies, efficacy, treatment

Partially replacing cyclophosphamide with bendamustine in combination with cyclosporine A improves survival and reduces xenogeneic graft-versus-host-disease

2022

cyclophosphamide, bendamustine, graft-versus-host disease, survival, cyclosporine a

Reply to Ewell and Abbotts

2022

academic discussion, literary analysis, critical evaluation, correspondence, debate

People

Profile

Richard Simpson

Collaboration(23)

H-H. Sherry Chow

Judith Gordon

Cynthia Thomson

Denise Roe

Bonnie LaFleur

Grants(20)

Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training Program

Exercise as an Immune Adjuvant for Gamma Delta T-cell Therapies in Hematologic Malignancies

Use of Humanized NSG mice to optimally balance GvHD and GvL against hematologic malignancies

Role for Myeloid Acid Ceramidase in Colon Inflammation and Cancer

Validation of Multisystem Countermeasures Protocol for Spaceflight during Antartica Winterover at Palmer Station

Publications(253)

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

Relationships between T-lymphocytes and physical function in adults with chronic lymphocytic leukemia: Results from the HEALTH4CLL pilot study

Multiagent Intratumoral Immunotherapy Can Be Effective in A20 Lymphoma Clearance and Generation of Systemic T Cell Immunity

Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice

The effect of physical exercise on anticancer immunity

Clonal kinetics and single-cell transcriptional profiles of T-cells mobilized to blood by acute exercise

Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2

Comparable Efficacy of Oral Bendamustine versus Intravenous Administration in Treating Hematologic Malignancies

Partially replacing cyclophosphamide with bendamustine in combination with cyclosporine A improves survival and reduces xenogeneic graft-versus-host-disease

Reply to Ewell and Abbotts