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Profile
Natalia Ignatenko
Associate Professor, Cellular and Molecular Medicine
Cellular & Molecular Medicine
Full Page
Overview
Research
More
Collaboration
(38)
H-H. Sherry Chow
Mutual work: 2 Grants﹒10 Proposals
Collaboration Details
Cynthia Thomson
Mutual work: 2 Grants﹒12 Proposals
Collaboration Details
Bonnie LaFleur
Mutual work: 3 Proposals
Collaboration Details
Denise Roe
Mutual work: 16 Proposals﹒3 Grants
Collaboration Details
David Besselsen
Mutual work: 5 Proposals﹒15 Publications﹒2 Grants
Collaboration Details
Page 1 of 8
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Grants
(8)
Targeting Polyamines to Suppress SARS-CoV-2 Related Disease
Active
·
2021
·
$103.8K / $230.7K
·
External
Principal Investigator (PI)
polyamines,
sars-cov-2,
disease suppression,
antiviral therapy,
drug development
Targeting Polyamines to Suppress SARS-CoV-2 Related Disease
2021
·
$568.6K / $614K
·
External
Principal Investigator (PI)
polyamines,
sars-cov-2,
disease suppression,
drug targeting,
viral infection
Role of Kallikrein 6 Expression and Secretion in Colon Cancer
2012
·
$1.4M / $1.6M
·
External
Principal Investigator (PI)
colon cancer,
kallikrein 6,
gene expression,
tumor progression,
biomarker discovery
Arizona Cancer Center - Cancer Center Support Grant
2009
·
$0 / $27.1M
·
External
Co-Investigator (COI)
oncology,
cancer research,
cancer care,
medical research,
grant funding
Dual Modality System for Imaging Colon Cancer in Mice
2009
·
$84.1K / $1.7M
·
External
Co-Investigator (COI)
imaging,
cancer,
colon,
mice,
modality
Page 1 of 2
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Publications
(49)
Recent
Digital Image analysis using Video microscopy of human-derived prostate cancer vs normaprostate organoids to assess migratory behavior on extracellular matrix proteins.
2023
digital image analysis,
video microscopy,
prostate cancer,
organoid research,
extracellular matrix
Difluoromethylornitine DFMO) suppresses pancreatic cells invasion by altering mutant K-RAS signaling
2023
pancreatic cancer,
mutant k-ras,
cell invasion,
dfmo,
signaling pathway
Kallikrein-related peptidase 6 contributes to the murine intestinal tumorigenesis driven by the mutant Adenomatous Polyposis Coli gene
2023
cancer,
genetics,
intestinal diseases,
enzyme biology,
mouse models
Kallikrein-Related Peptidase 6 KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis
2022
cancer,
metastasis,
kallikrein-related peptidase 6,
colon cancer,
cell phenotype
Synthesis and structure–activity relationships of N-4-benzamidino) oxazolidinones–potent and selective inhibitors of kallikrein-related peptidase 6
2019
drug development,
enzyme inhibitors,
medicinal chemistry,
structure-activity relationships,
peptidase inhibitors
Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility grou A2 protein
2019
cancer,
proteases,
tumorigenesis,
oncology,
protein induction
Detection of enzyme activity and inhibition during studies in solution, in vitro, and in vivo with catalyCEST MRI
2018
enzyme activity,
inhibition,
catalycest mri,
in vitro,
in vivo
Does Mutated Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?
2018
oncogene mutation,
colon cancer,
chemoprevention,
sulindac,
effect attenuation
Specific microRNA-mRNA regulatory network of colon cancer invasion regulated by tissue kallikrein-related peptidase 6
2017
microrna,
mrna,
colon cancer,
regulatory network,
tissue kallikrein-related peptidase 6
Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways
2015
pancreatic cancer,
metastasis,
gtpase signaling,
k-ras,
invasion
