Precautions in Place as Student-Athletes Return to Campus

UA Team Uncovers Promising Lead in Genetic Approach to Treating Glioblastoma

Supercomputers Could Improve Cancer Diagnostics

UA Researcher in PBS Series on Early Humans

KGUN-TV Series on UA Research

A Boost for Precision Health: UA Genetics Core Accredited for Health Care Services

UA Contributes to Largest Survey of Great Ape Genome Diversity

Graduate Interdisciplinary Programs Build Collaboration, Productivity

Human Y Chromosome Much Older Than Previously Thought

UA Geneticists Find Causes for Severe Childhood Epilepsies

Evolution of Religious Patriarchy as a Mate-Guarding Strategy?

Genome Sequencing Finds Unknown Cause of Epilepsy

Ancient Humans Were Mixing it Up

UA's BIO5 Institute Hosting International RECOMB 2009 Conference

New Genetic Research Indicates Jewish Priesthood Has Multiple Lineages

This Week at the UA April 3-7

Genographic Project Director, UA Colleague to Speak on Campus

The Biggest Family Tree Ever

Genes Expose Secrets of Sex on the Side

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Clinical Characteristics and Treatment Experience of Individuals with SCN8A Developmental and Epileptic Encephalopathy (SCN8A-DEE): Findings from an Online Caregiver Survey

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Greater female than male resilience in mortality and morbidity in the Scn8a mouse model of pediatric epilepsy

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Whole exome sequencing and co-expression analysis identify an SCN1A variant that modifies pathogenicity in a family with Genetic Epilepsy and Febrile Seizures Plus (GEFS+)

SCN8A Epilepsy, Developmental Encephalopathy, and Related Disorders

Rare tumor-normal matched whole exome sequencing identifies novel genomic pathogenic germline and somatic aberrations

Whole exome sequencing of rare tumor and matched germline DNA identifies somatic and inherited variants of clinical significance

Hippocampal RNA Expression Gene Sets and Biological Pathways with Prognostic Value for Seizure Outcome Following Anterior Temporal Lobectomy with Amygdalohippocampectomy

Variable patterns of mutation density among Na V 1.1, Na V 1.2 and Na V 1.6 point to channel-specific functional differences associated with childhood epilepsy.

A multi-disciplinary clinic for SCN8A-related epilepsy

Stephen L. Zegura (2 July 1943–26 May 2019)

The spectrum of intermediate SCN 8A‐related epilepsy

Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency

Influence of age at seizure onset on the acquisition of neurodevelopmental skills in an SCN8A cohort

Identification of African-Specific Admixture between Modern and Archaic Humans

Genomic evidence of local adaptation to climate and diet in indigenous Siberians

Substructured population growth in the ashkenazi jews inferred with approximate bayesian computation

Leukocyte expression profiles reveal gene sets with prognostic value for seizure-free outcome following stereotactic laser amygdalohippocampotomy

Exome sequencing provides evidence of polygenic adaptation to a fat-rich animal diet in indigenous Siberian populations

Rare variants of small effect size in neuronal excitability genes influence clinical outcome in Japanese cases of SCN1A truncation-positive Dravet Syndrome

Model-based analyses of whole genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies

Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection

Isolation, Contact and Social Behavior Shaped Genetic Diversity in West Timor

Human hybrids

An African American paternal lineage adds an extremely ancient root to the human Y chromosome phylogenetic tree

Neandertal origin of genetic variation at the cluster of OAS immunity genes

De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP

Global genetic variation at OAS1 provides evidence of archaic admixture in Melanesian populations

A haplotype at STAT2 Introgressed from neanderthals and serves as a candidate of positive selection in Papua New Guinea

An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal resequencing data

Increased resolution of Y chromosome haplogroup T defines relationships among populations of the Near East, Europe, and Africa

Major east-west division underlies Y chromosome stratification across Indonesia

Autosomal and X-linked single nucleotide polymorphisms reveal a steep Asian-Melanesian ancestry cline in eastern Indonesia and a sex bias in admixture rates

Autosomal resequence data reveal Late Stone Age signals of population expansion in sub-Saharan African foraging and farming populations

Intergenic DNA sequences from the human X chromosome reveal high rates of global gene flow

Contrasting signatures of population growth for mitochondrial DNA and Y chromosomes among human populations in Africa

Testing for archaic hominin admixture on the X chromosome: model likelihoods for the modern human RRM2P4 region from summaries of genealogical topology under the structured coalescent

Male dominance rarely skews the frequency distribution of Y chromosome haplotypes in human populations

Joint match probabilities for Y chromosomal and autosomal markers

New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree

Recombination-filtered genomic datasets by information maximization

A Polynesian motif on the Y chromosome: population structure in remote Oceania

Coevolution of languages and genes on the island of Sumba, eastern Indonesia

Reconstructing human origins in the genomic era

Genetic structure among 38 populations from the United States based on 11 U.S. core Y chromosome STRs

The beta -globin recombinational hotspot reduces the effects of strong selection around HbC, a recently arisen mutation providing resistance to malaria

Contrasting patterns of Y chromosome and mtDNA variation in Africa: evidence for sex-biased demographic processes

Deep haplotype divergence and long-range linkage disequilibrium at xp21.1 provide evidence that humans descend from a structured ancestral population

Balinese Y-chromosome perspective on the peopling of Indonesia: genetic contributions from pre-neolithic hunter-gatherers, Austronesian farmers, and Indian traders

High-resolution SNPs and microsatellite haplotypes point to a single, recent entry of Native American Y chromosomes into the Americas

Genetic evidence for unequal effective population sizes of human females and males

Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males

European ACP1*C allele has recessive deleterious effects on early life viability

Nucleotide variation at Msn and Alas2, two genes flanking the centromere of the X chromosome in humans

High levels of Y-chromosome differentiation among native Siberian populations and the genetic signature of a boreal hunter-gatherer way of life

Gene flow from the Indian subcontinent to Australia: evidence from the Y chromosome