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Michael D. L. Johnson received his bachelors from Duke University. He obtained a Ph.D. in Biochemistry and Biophysics from the University of North Carolina at Chapel Hill, where he studied the effects of calcium on bacterial motility and attachment under the mentorship of Matthew Redinbo. For his postdoctoral training, Michael Johnson went to St. Jude Children’s Research Hospital in order to work with Jason Rosch on metal homeostasis of Streptococcus pneumoniae and subsequently with Douglas Green on the mechanisms of LC3-associated phagocytosis. Michael Johnson joined the faculty of the University of Arizona in 2016.Show Less
VOSviewer
Courses
- PMMMHIPrinciples and Molecular Mechanisms of Microbe-Host Interactions
- MMIMedical Microbiology and Immunology
Grants
- REU Site: The National Summer Undergraduate Research Project
Principal Investigator (PI)
2022
$1.0M
Active - National Summer Undergraduate Research Program
Principal Investigator (PI)
2022
$273.5K
Active - RAPID: The National Summer Undergraduate Research Project (NSURP), a Virtual Platform for Engaging Underrepresented Minorities in STEM
Principal Investigator (PI)
2021
$323.1K
Active - RAPID: The National Summer Undergraduate Research Project (NSURP), a Virtual Platform for Engaging Underrepresented Minorities in STEM
Principal Investigator (PI)
2021
$76.8K
Active - RAPID: The National Summer Undergraduate Research Project (NSURP), a Virtual Platform for Engaging Underrepresented Minorities in STEM
Principal Investigator (PI)
2021
$46.3K
Active - CC16: A Link between Airway Infection and Obstructive Lung Disease
Co-Investigator (COI)
2019
$2.0M
Active - Elucidating the Orchestrated Bacterial Response to Copper Toxicity
Principal Investigator (PI)
2018
$2.5M
Active - Elucidating the Orchestrated Bacterial Response to Copper Toxicity
Principal Investigator (PI)
2018
$122.9K
Active - Elucidating the Orchestrated Bacterial Response to Copper Toxicity - Diversity Supplement (UGrad)
Principal Investigator (PI)
2018
$13.0K
Active - Transcriptional Regulation of Antibody Responses and Immunity
Key Personnel (KP)
2023
$531.0K
Technologies / Patents
News
- Cascading Colorado River cuts bring focus to future of Arizona agriculture
2022
- Student views of racism in medicine a catalyst for change
2022
- Beyond Juneteenth: A yearlong celebration of Black history, culture and contributions
2022
- Outstanding Seniors to be Honored During Virtual Commencement
2020
- UArizona Researchers Pivot to Tackle COVID-19
2020
- Exploring Copper's Potential as Antibiotic
2019
- In the Age of Social Media, He's a New Kind of Scientist
2017
- Health Sciences Education Building Under Construction
2010
- Highlighting UA Medical School, Phoenix Gets Honor
2009
Publications (43)
Recent
- The role of CopA in Streptococcus pyogenes copper homeostasis and virulence
2023
- CC16 Induces Airway Epithelial Cell-Driven SPLUNC1 Expression by Signaling through VLA-2
2023
- Novel dithiocarbamate derivatives are effective copper-dependent antimicrobials against Streptococcal species
2023
- em N /em , em N /em -Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance
2022
- Compounds derived from N,N-dimethyldithiocarbamate are effective copper-dependent antimicrobials against Streptococcus pneumoniae
2022
- ,-Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance
2022
- National Summer Undergraduate Research Project (NSURP): A Virtual Research Experience to Deliver REAL (Retention, Equity, Access, and Life-Changing) Outcomes for Underrepresented Minorities in STEM
2022
- A quantitative enzyme-linked immunoassay (ELISA) to approximate complement-fixing antibody titers in serum from patients with coccidioidomycosis
2021
- Demonstration of N , N -Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens
2021
- CC16 Binding to α4β1 Integrin Protects against Mycoplasma pneumoniae Infection.
2021
- Dynamic Pneumococcal Genetic Adaptations Support Bacterial Growth and Inflammation during Coinfection with Influenza.
2021
- Media Matters, Examining Historical and Modern Streptococcus pneumoniae Growth Media and the Experiments They Affect
2021
- Extensive evaluation of ATAC-seq protocols for native or formaldehyde-fixed nuclei
2021
- Cc16 binding to α4β1 integrin protects against mycoplasma pneumoniae infection
2021
- Mentoring to Foster a Diverse Future
2020
- mSphere Highlights Black In Microbiology Week
2020
- em mSphere /em Highlights Black In Microbiology Week
2020
- Highlights Black In Microbiology Week
2020
- Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors
2020
- Crowdsourcing virtual summer research opportunities to support minorities in microbiology
2020
- CC16 Binding to α4β1 Integrin (VLA-4) Protects Against Infection
2020
- Characterization of consensus operator site for Streptococcus pneumoniae copper repressor, CopY
2019
- Characterization of pneumococcal copper repressor CopY-DNA repression
2019
- mSphere of Influence: Hiring of Underrepresented Minority Assistant Professors in Medical School Basic Science Departments Has a Long Way To Go
2019
- Characterization of consensus operator site for Streptococcus pneumoniae copper repressor
2019
- Dynamic pneumococcal genetic adaptations support bacterial growth and inflammation during coinfection with influenza
2019
- LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.
2018
- Copper Chaperone CupA and Zinc Control CopY Regulation of the Pneumococcal em cop /em Operon
2017
- Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae
2016
- Science Sound Bites, a Podcast for STEM Curriculum Supplementation †
2016
- An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens
2016
- Copper intoxication inhibits aerobic nucleotide synthesis in Streptococcus pneumoniae
2015
- Role of copper efflux in pneumococcal pathogenesis and resistance to macrophage-mediated immune clearance
2015
- Characterization of NAD salvage pathways and their role in virulence in Streptococcus pneumoniae
2015
- Calcium binding properties of the Kingella kingae PilC1 and PilC2 proteins have differential effects on type IV pilus-mediated adherence and twitching motility
2013
- The roles of transition metals in the physiology and pathogenesis of Streptococcus pneumoniae
2013
- Mutation of the conserved calcium-binding motif in Neisseria gonorrhoeae PilC1 impacts adhesion but not piliation
2013
- Pseudomonas aeruginosa PilY1 binds integrin in an RGD- and calcium-dependent manner
2011
- Crystal structure analysis reveals Pseudomonas PilY1 as an essential calcium-dependent regulator of bacterial surface motility
2010
- Erratum: Crystal structure analysis reveals Pseudomonas PilY1 as an essential calcium-dependent regulator of bacterial surface motility (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 3 (1065-1070) DOI:10.1073/pnas.0911616107)
2010
- The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor
2008
- Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin
2007