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Picture of Jared Churko

Jared Churko

Assistant Professor, Physiological Sciences - GIDP | Assistant Professor, Biomedical Engineering | Director, iPS Cell Core | Assistant Professor, Genetics - GIDP | Associate Professor, BIO5 Institute | Member of the Graduate Faculty | Associate Professor, Cellular and Molecular Medicine

Cellular & Molecular Medicine

Collaboration(40)

Denise Roe
Shenfeng Qiu
Janko Nikolich
Megha Padi
Ritu Pandey

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Grants(6)

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Publications(71)

Recent

Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction

2024

cardiomyopathy, genetic mutation, cardiomyocyte dysfunction, neonatal

Pituitary Neuroendocrine Tumor Organoids Generated from Induced Pluripotent Stem Cells Reveal the Dysregulation of Cell Lineage Differentiation in Cushing’s Disease

2024

stem cells, cancer biology, endocrinology, cell differentiation, tumor biology

Insulin growth factor promotes a fattyfibro phenotype in epicardial cells derived from arrhythmogenic cardiomyopathy iPSCs

2024

insulin growth factor, cardiomyopathy, epicardial cells, arrhythmogenic, ipscs

OR20-05 Generation Of CDH23-mutated Pituitary Neuroendocrine Tumor Organoids From Induced Pluripotent Stem Cells To Model Cushing’s Disease Pathogenesis

2023

stem cells, neuroendocrine, organoids

Genetically engineered human pituitary corticotroph tumor organoids exhibit divergent responses to glucocorticoid receptor modulators

2023

genetic engineering, tumor biology, corticotroph, glucocorticoid receptors, organoids

Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

2023

hipsc-modeling, atrial fibrillation, titin variant, cell-type-specific, patient-specific

Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts

2023

proteomics, cardiomyocytes, heart failure, cell surface proteins, biomarkers

Generation of an iPSC line from a Pontocerebellar Hypoplasia 1B patient harboring a homozygous c. 395 A> C mutation in EXOSC3 along with a family matched control

2022

stem cells, genetics, neuroscience, disease modeling, cell biology

Development of Human Pituitary Adenoma Organoids to Facilitate Effective Targeted Treatments of Cushing's Disease.

2022

pituitary adenoma, organoids, cushing's disease, targeted treatments, development

PO-645-04 GENERATION AND MULTIPARAMETRIC TESTING OF ENGINEERED HEART TISSUE

2022

tissue engineering, heart regeneration, biomedical engineering, cell culture, biomechanics