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Courses
- CMPCellular and Molecular Physiology
- BBEBiology for Biomedical Engineering
- SNSystems Neuroscience
- RMPResearch Methods in Physiology
- HPHuman Physiology
- PCMNPrinciples of Cellular and Molecular Neurobiology
- PBEPhysiology for Biomedical Engineering
Grants
- Retinal Neuronal Signaling in Early Diabetes
Principal Investigator (PI)
2021
$743.4K
Active - Investigation and Modulation of Inner Retinal Dysfunction in Diabetes
Principal Investigator (PI)
2021
$85.0K
Active - CAREER: The Role of Inhibition in Light Adaptation of the OFF Retinal Pathway
Principal Investigator (PI)
2016
$900.0K
Active - IPA for Michael Flood: Dopamine Treatments for Diabetic Retinopathy
Principal Investigator (PI)
2019
$15.3K
- Retinal Neuronal Signaling in Early Diabetes
Principal Investigator (PI)
2015
$1.7M
- Testing the Role of Dopamine as a Potential Treatment for Diabetic Retinal Dysfunction
Principal Investigator (PI)
2015
$198.3K
- Novel Mechanisms and Roles of Inhibition in Retinal Light Adaptation
Principal Investigator (PI)
2015
$49.9K
- Identification of Novel Mechanisms of Diabetic Retinal Disease
Co-Investigator (COI)
2014
$166.0K
- Neuronal Signaling and Survival in Early Diabetic Retinal Disease
Principal Investigator (PI)
2014
$50.0K
- Identification of Early Mechanisms of Diabetic Retinal Damage
Principal Investigator (PI)
2013
$109.8K
News
- Three UA Researchers Earn NSF CAREER Grants
2016
- UA Researchers Explore Root of Diabetic Retinal Damage
2013
Publications (33)
Recent
- Visual Dysfunction in Diabetes.
2023
- span style= font-size:11pt; Dopamine receptor effects on in vitro ERGs are compromised in early diabetes /span
2023
- span style= font-size:11pt; Visual Dysfunction in Diabetes /span
2023
- Impaired light adaptation of ON-sustained ganglion cells in early diabetes is attributable to diminished dopamine D4 receptor sensitivity
2022
- Impaired Light Adaptation of ON-Sustained Ganglion Cells in Early Diabetes Is Attributable to Diminished Response to Dopamine D4 Receptor Activation
2022
- Dopamine D1 and D4 receptors contribute to light adaptation in ON-sustained retinal ganglion cells
2021
- The effects of early diabetes on inner retinal neurons
2020
- Early diabetes impairs ON sustained ganglion cell light responses and adaptation without cell death or dopamine insensitivity
2020
- Inhibitory components of retinal bipolar cell receptive fields are differentially modulated by dopamine D1 receptors
2020
- Dopamine D1 receptor activation reduces local inner retinal inhibition to light-adapted levels
2019
- Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells.
2019
- Dopamine D1 receptor activation contributes to light-adapted changes in retinal inhibition to rod bipolar cells
2018
- Early Retinal Neuronal Dysfunction in Diabetic Mice: Reduced Light-Evoked Inhibition Increases Rod Pathway Signaling
2016
- Light adaptation alters inner retinal inhibition to shape OFF retinal pathway signaling
2016
- Different types of retinal inhibition have distinct neurotransmitter release properties
2015
- Slow changes in Ca2(+) cause prolonged release from GABAergic retinal amacrine cells
2013
- Inhibition to retinal rod bipolar cells is regulated by light levels
2013
- Light adaptation alters the source of inhibition to the mouse retinal OFF pathway
2013
- Rod Vision Is Controlled by Dopamine-Dependent Sensitization of Rod Bipolar Cells by GABA
2011
- Nonlinear interactions between excitatory and inhibitory
2011
- Nonlinear interactions between excitatory and inhibitory retinal synapses control visual output
2011
- Multiple pathways of inhibition shape bipolar cell responses in the retina
2011
- Interneuron circuits tune inhibition in retinal bipolar cells
2010
- Visual Signal Processing in the Inner Retina
2008
- Development of presynaptic inhibition onto retinal bipolar cell axon terminals is subclass-specific
2008
- Presynaptic inhibition differentially shapes transmission in distinct circuits in the mouse retina
2007
- Receptor and transmitter release properties set the time course of retinal inhibition
2006
- GABAA, GABAC and glycine receptor-mediated inhibition differentially affects light-evoked signalling from mouse retinal rod bipolar cells
2006
- Retinal GABA receptors and visual processing: a model system for presynaptic inhibition
2006
- GABA C receptor-mediated inhibition in the retina
2004
- Mechanisms for the modulation of native glycine receptor channels by ethanol
2004
- Differential effects of ethanol on GABAA and glycine receptor-mediated synaptic currents in brain stem motoneurons
2003
- Developmental changes in the modulation of synaptic glycine receptors by ethanol
2000