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Dr. Bonnie Hurwitz is an Associate Professor of Biosystems Engineering at the University of Arizona and BIO5 Institute Fellow. She has worked as a computational biologist for nearly two decades on interdisciplinary projects in both industry and academia. Her research on the human/earth microbiome incorporates large-scale –omics datasets, high-throughput computing, and big data analytics towards research questions in “One Health”. In particular, Dr. Hurwitz is interested in the relationship between the environment, microbial communities, and their hosts. Dr. Hurwitz is well-cited for her work in computational biology in diverse areas from plant genomics to viral metagenomics.

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Research Opportunities
  • Undergrad Research Opp Paid, Volunteer, For Credit

    Grant: Not Listed

    metagenomics, genomics, microbes, viruses, bioinformatics, computing, big data, high performance com...
Courses
  • IBATBATCUREA
    Introduction to Biosystems Analytics & Technology (BAT) using the CURE Approach

  • MFGE
    Metagenomics: From Genes to Ecosystems

  • BA
    Biosystems Analytics

Grants
  • Funding agency logo
    Leveraging the Microbiome, Local Admixture, and Machine Learning to Optimize Anticoagulant Pharmacogenomics in Medically Underserved Patients

    Co-Investigator (COI)

    2021

    $1.4M
    Active
  • Funding agency logo
    NRT-URoL: BRIDGES - Building Resources for InterDisciplinary training in Genomic and Ecosystem Sciences

    Co-Investigator (COI)

    2020

    $3.0M
    Active
  • Funding agency logo
    I-Corps: Rapid Home Microbiome Diagnostics Tests

    Principal Investigator (PI)

    2020

    $50.0K
    Active
  • Funding agency logo
    Harmonizing Marine Microbiome Datasets with Ontology Standards and Infrastructure for the National Microbiome Data Collaborative

    Principal Investigator (PI)

    2019

    $260.3K
  • Funding agency logo
    Metagenomic and Metabolomic Analysis of the Structure and Function of the Human Gut Microbiome in Congenital Heart

    Co-Investigator (COI)

    2019

    $153.5K
  • Funding agency logo
    muSCOPE: A Comprehensive Repository of SCOPE 'Omics Data and Associated Metadata

    Principal Investigator (PI)

    2018

    $131.7K
  • Funding agency logo
    Collaborative Proposal: Earthcube Building Blocks: Planet Microbe: Enabling the Discovery and Integration of Oceanographic 'omics, Environmental and Physiochemical Data Layers

    Principal Investigator (PI)

    2017

    $873.0K
  • Funding agency logo
    CIF21 DIBBs: PD: Accelerating Comparative Metagenomics Through an Ocean Cloud Commons

    Principal Investigator (PI)

    2017

    $588.2K
  • Funding agency logo
    CIF21 DIBBs: PD: Accelerating Comparative Metagenomics through an Ocean Cloud Commons

    Principal Investigator (PI)

    2017

    $92.1K
  • Funding agency logo
    Illuminating the Pathways to Carbon Liberation: A Systems Approach to Characterizing the Consequential Unknowns of Carbon Transformation and Loss from Thawing Permafrost Peatlands

    Co-Investigator (COI)

    2016

    $708.2K
Technologies / Patents
      News
      • $3M Grant Helps Students Bridge Sciences to Solve the World's Biggest Problems

        2020

      • 'Rainforest Under Glass' Kissed by Rain After Two-Month Drought

        2019

      • Researcher Uses 'Shotgun Sequencing' to Study Microorganisms

        2018

      • Between Netflix and Big Data

        2015

      • Virtual Network to Help Scientists Go Viral

        2015

      • UA Scientists Help Discover Most Abundant Ocean Virus

        2013

      • UA's Multi-Million Dollar Research Initiative Gets Booster

        2012

      • Open Access Week 2012: Raising Awareness at the UA

        2012

      Publications (54)
      Recent
      • Network analysis reveals dysregulated functional patterns in type II diabetic skin

        2022

      • An adaptable and non-invasive method for tracking Bifidobacterium animalis subspecies lactis 420 in the mouse gut

        2021

      • Correction for Vangay et al., Microbiome Metadata Standards: Report of the National Microbiome Data Collaborative's Workshop and Follow-On Activities

        2021

      • Planet Microbe: a platform for marine microbiology to discover and analyze interconnected 'omics and environmental data

        2021

      • Role of the gut microbiome in cardiovascular drug response: The potential for clinical application

        2021

      • Cyanolichen microbiome contains novel viruses that encode genes to promote microbial metabolism

        2021

      • Ontology-Enriched Specifications Enabling Findable, Accessible, Interoperable, and Reusable Marine Metagenomic Datasets in Cyberinfrastructure Systems

        2021

      • Microbiome Metadata Standards: Report of the National Microbiome Data Collaborative's Workshop and Follow-On Activities

        2021

      • The dynamic wound microbiome

        2020

      • Metagenomic Next-Generation Sequencing in Clinical Microbiology

        2020

      • PuMA: A papillomavirus genome annotation tool

        2020

      • Future Directions of the Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Program

        2020

      • Metagenomic exploration of lichen thalli reveals novel viral communities

        2020

      • COVID-19 pandemic reveals the peril of ignoring metadata standards

        2020

      • Erratum to: iMicrobe: Tools and data-driven discovery platform for the microbiome sciences

        2019

      • Identification and quantitation of clinically relevant microbes in patient samples: Comparison of three k-mer based classifiers for speed, accuracy, and sensitivity

        2019

      • EarthCube: A Community-Driven Cyberinfrastructure for the Geosciences ndash;A Progress Report

        2019

      • iMicrobe: Tools and data-dreaiven discovery platform for the microbiome sciences

        2019

      • The Promises and Pitfalls of Machine Learning for Detecting Viruses in Aquatic Metagenomes

        2019

      • Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer

        2019

      • Minimum Information about an Uncultivated Virus Genome (MIUViG)

        2018

      • Libra: scalable k-mer based tool for massive all-vs-all metagenome comparisons

        2018

      • Libra: Improved Partitioning Strategies for Massive Comparative Metagenomics Analysis

        2018

      • The Relationship of Host Genetics and the Microbiome in Colon Cancer.

        2018

      • iVirus: facilitating new insights in viral ecology with software and community data sets imbedded in a cyberinfrastructure

        2017

      • Viral to metazoan marine plankton nucleotide sequences from the Tara Oceans expedition

        2017

      • Phage hunters: Computational strategies for finding phages in large-scale 'omics datasets

        2017

      • 16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria

        2017

      • Seasonal time bombs: dominant temperate viruses affect Southern Ocean microbial dynamics

        2016

      • Skin and Soft Tissue Infections

        2016

      • Method-centered digital communities on protocols.io for fast-paced scientific innovation

        2016

      • Computational prospecting the great viral unknown

        2016

      • Viral metabolic reprogramming in marine ecosystems

        2016

      • Protocols.io: Virtual Communities for Protocol Development and Discussion

        2016

      • VirSorter: mining viral signal from microbial genomic data

        2015

      • Set Phages to Stun: Reducing the Virulence of Staphylococcus aureus in Diabetic Foot Ulcers

        2015

      • Microbiology of diabetic foot infections: from Louis Pasteur to 'crime scene investigation'

        2015

      • Draft Genome Sequence of the Ale-Fermenting Saccharomyces cerevisiae Strain GSY2239

        2015

      • The quest for tissue repair’s holy grail: the promise of wound diagnostics or just another fishing expedition?

        2015

      • Depth-stratified functional and taxonomic niche specialization in the 'core' and 'flexible' Pacific Ocean Virome

        2015

      • Three-dimensional printing surgical instruments: are we there yet?

        2014

      • Modeling ecological drivers in marine viral communities using comparative metagenomics and network analyses

        2014

      • Metabolic reprogramming by viruses in the sunlit and dark ocean

        2013

      • The Pacific Ocean virome (POV): a marine viral metagenomic dataset and associated protein clusters for quantitative viral ecology

        2013

      • Evaluation of methods to concentrate and purify ocean virus communities through comparative, replicated metagenomics

        2012

      • Rice structural variation: a comparative analysis of structural variation between rice and three of its closest relatives in the genus Oryza

        2010

      • Rapid genomic characterization of the genus vitis

        2010

      • Dynamics of genome evolution in facultative symbionts of aphids

        2010

      • Species trees from highly incongruent gene trees in rice

        2009

      • A first-generation haplotype map of maize

        2009

      • Construction, alignment and analysis of twelve framework physical maps that represent the ten genome types of the genus Oryza

        2008

      • Gramene: a growing plant comparative genomics resource

        2008

      • Integration of hybridization-based markers (overgos) into physical maps for comparative and evolutionary explorations in the genus Oryza and in Sorghum

        2006

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