Profile

Ashley Snider

Professor, Cancer Biology - GIDP | Member of the Graduate Faculty | Professor, BIO5 Institute | Professor, Nutritional Sciences and Wellness

Nutritional Sci Wellness - RES

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Overview

Research

Collaboration(16)

Page 1 of 4

Grants(5)

Role for Myeloid Acid Ceramidase in Colon Inflammation and Cancer
Active·2022·$884.7K / $983K·
External
Principal Investigator (PI)
colon cancer, inflammation, myeloid cells, ceramidase, role in cancer development
Sphingolipids, Dietary Fatty Acids, and Intestinal Pathophysiology
Active·2021·$834.4K / $981.6K·
External
Principal Investigator (PI)
lipids, dietary, intestinal health, fatty acids, pathophysiology
The novel therapeutic targets to prevent right ventricle failure in pulmonary arterial hypertension
2023·$0 / $231K·
External
Key Personnel (KP)
therapeutic targets, right ventricle, pulmonary arterial hypertension, prevention, novel
Novel Mouse Model for Charcot-Marie Tooth Disease
2020·$153.5K·
External
Principal Investigator (PI)
mouse model, charcot-marie tooth disease, novel, neurological disorder, genetic disease
Developing Animal Models to Dissociate Lysosomal from Inflammatory Functions of Acid Sphingomyelinase
2020·$152.1K·
External
Principal Investigator (PI)
animal models, lysosomal function, inflammatory functions, acid sphingomyelinase, dissociation

Publications(49)

Recent

PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer

2023

prostate cancer, lipid droplets, proliferation, survival, cell growth

A Novel HSPB1 Mouse Model of Charcot-Marie-Tooth Disease

2023

neuroscience, genetics, mouse model, neuromuscular disorders, hspb1

Targeting sphingosine kinase 1 in p53KO thymic lymphoma

2023

cancer, sphingolipids, enzyme inhibition, p53, lymphoma

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands

2023

lipid signaling, endothelial function, lung diseases, cell surface receptors, vascular biology

strong Expression of ceramide synthases in mice and their roles in regulating acyl-chain sphingolipids: A framework for baseline levels and future implications in aging and disease. strong

2023

sphingolipid metabolism, aging, disease regulation, ceramide synthases, mice model

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury

2022

ceramidase deficiency, acute kidney injury, cisplatin, kidney protection, neutral ceramidase

1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase

2022

cancer metabolism, cell signaling, adaptive response, proteolysis, sphingolipid metabolism

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer

2021

breast cancer, metastasis, lung, sphingosine kinase 1, mmtv-pymt mouse model

GrouIIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality

2021

covid-19, phospholipase a2, pathobiology, mortality, grouiia

n-6 High Fat Diet Induces Gut Microbiome Dysbiosis and Colonic Inflammation

2021

gut microbiome, diet-induced inflammation, high-fat diet, colonic inflammation, dysbiosis

People

Profile

Ashley Snider

Collaboration(16)

H-H. Sherry Chow

Bonnie LaFleur

Megha Padi

Anne Cress

Richard Simpson

Grants(5)

Role for Myeloid Acid Ceramidase in Colon Inflammation and Cancer

Sphingolipids, Dietary Fatty Acids, and Intestinal Pathophysiology

The novel therapeutic targets to prevent right ventricle failure in pulmonary arterial hypertension

Novel Mouse Model for Charcot-Marie Tooth Disease

Developing Animal Models to Dissociate Lysosomal from Inflammatory Functions of Acid Sphingomyelinase

Publications(49)

PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer

A Novel HSPB1 Mouse Model of Charcot-Marie-Tooth Disease

Targeting sphingosine kinase 1 in p53KO thymic lymphoma

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands

strong Expression of ceramide synthases in mice and their roles in regulating acyl-chain sphingolipids: A framework for baseline levels and future implications in aging and disease. strong

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury

1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer

GrouIIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality

n-6 High Fat Diet Induces Gut Microbiome Dysbiosis and Colonic Inflammation