The University of Arizona
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Jacob Schwartz

Associate Professor, Neuroscience - GIDP | Associate Professor, BIO5 Institute | Assistant Professor, Chemistry and Biochemistry - Med | Associate Research Professor, Pharmacology - (Research Series Track) | Member of the Graduate Faculty | Associate Professor, Cancer Biology - GIDP

Pharmacology
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10+ Collaborators
$4.6M / $4.6M Funding
9+ Grants
10+ Publications
6+ Courses
10+ Tech/Patents

Research Area

cell biology, molecular biology, cancer, gene expression, gene regulation, biochemistry, protein interaction, rna binding, transcription regulation, protein aggregation

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    Recent

    Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks

    2024

    Direct and indirect effects of CYTOR lncRNA regulate HIV gene expression

    2024

    Binding of the nuclear ribonucleoprotein family member FUS to RNA prevents R-looRNA:DNA hybrid structures

    2023
    rna binding, dna-rna interaction, nuclear ribonucleoproteins, r-loop formation, fus protein

    Fusion protein EWS-FLI1 is incorporated into a protein granule in cells

    2021
    protein regulation, cell biology, gene fusion, protein aggregation, oncology

    Isolating and Analyzing Protein Containing Granules from Cells

    2021
    proteomics, cell biology, biochemistry, cellular imaging, cell fractionation

    Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

    2021
    traumatic injury, nucleocytoplasmic transport, tdp-43 pathology, brain trauma, neurodegeneration

    Determining protein structure with tyrosine bioconjugation

    2020

    Discriminating changes in protein structure using tyrosine conjugation

    2020
    protein structure, chemical modifications, conjugation analysis, protein characterization, biological assays

    Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage

    2020
    protein-protein interactions, dna damage, neurodegeneration, gene regulation, cellular stress response

    TDP-43 regulates transcription at protein-coding genes and Alu retrotransposons

    2019
    transcription regulation, protein-coding genes, tdp-43, alu retrotransposons, gene regulation

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    • Proteins and Enzymes

    • Biochemistry of Nucleic Acids

    • Nucleic Acids, Metabolism, and Signaling

    • Introduction to Biochemical Research

    • Metabolic Biochemistry

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    Jacob Schwartz | KMap Profile - Institutional Knowledge Map (KMap)