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Jayati Chakrabarti
Associate Scientific Investigator
Cellular & Molecular Medicine
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Research Area
cancer,
organoids,
immunotherapy,
pancreatic cancer,
gastric cancer,
immune response,
gastric,
tumor microenvironment,
cancer immunotherapy,
cell signaling,
helicobacter pylori,
cell biology,
organoid models,
injury response,
gene expression,
hedgehog signaling,
gastric regeneration,
regeneration,
gastric epithelium,
organoid,
tumor biology,
molecular biology,
targeted therapy,
cancer research,
immunology,
cancer biology,
stem cells,
neuroendocrine,
neuroendocrine tumors,
cushing's disease
Grants
(1)
The National Biorepository and Resource for Pituitary Neuroendocrine Tumor Translational Research (BioPitNeT)
Active
·
2024
·
$284.5K / $2.8M
·
External
Co-Investigator (COI)
biorepository,
pituitary,
neuroendocrine,
tumor,
translational research
Publications
(108)
Recent
Pituitary Neuroendocrine Tumor Organoids Generated from Induced Pluripotent Stem Cells Reveal the Dysregulation of Cell Lineage Differentiation in Cushing’s Disease
2024
stem cells,
cancer biology,
endocrinology,
cell differentiation,
tumor biology
Tu1211 CABOZANTINIB INCREASES THE EFFICACY OF PEMBROLIZUMAB IN HUMAN PANCREATIC DUCTAL ADENOCARCINOMA ORGANOID COCULTURES
2024
cancer immunotherapy,
pancreatic cancer,
drug combination,
organoid models,
precision medicine
8773 CD44 Variant Isoforms Expressed Within PAX7/SOX2-Positive Pituitary Neuroendocrine Tumors Attribute to Therapy Resistance and Recurrence of Cushing’s Disease
2024
recurrence
Cabozantinib changes the tumor microenvironment to increase the efficacy of immunotherapy in refractory metastatic pancreatic ductal adenocarcinoma
2024
immunotherapy,
pancreatic cancer,
tumor microenvironment,
metastatic cancer
166 Development of non-model organoids in animal research: A paradigm shift in in vitro models
2024
organoid development,
animal research,
paradigm shift
Cabozantinib changes the landscape of the pancreatic tumor microenvironment and improves the efficacy of pembrolizumab
2024
pancreatic cancer,
immunotherapy,
tumor microenvironment,
efficacy
Su1202 TARGETING THE CD44 VARIANT ISOFORMS USING A NOVEL CDC-LIKE PROTEIN KINASE INHIBITOR TO IMPROVE THE EFFICACY OF STANDARD-OF-CARE THERAPY FOR PANCREATIC DUCTAL ADENOCARCINOMA
2024
cancer,
therapy,
protein kinase,
pancreatic,
targeted therapy
SAT625 The EGF-TBX19-EGFR Positive Feedback LooRegulates The Expression Of The CD44v9/SLC7A11 Antioxidant System Within Corticotroph Pituitary Neuroendocrine Tumors
2023
gene regulation,
neuroendocrine tumors
OR20-05 Generation Of CDH23-mutated Pituitary Neuroendocrine Tumor Organoids From Induced Pluripotent Stem Cells To Model Cushing’s Disease Pathogenesis
2023
stem cells,
neuroendocrine,
organoids
Genetically Engineered Human Pituitary Corticotroph Tumor Organoids Exhibit Divergent Responses To Glucocorticoid Receptor Modulators
2022
genetic engineering,
hormone regulation,
tumor research,
organoid cultures,
drug response
Collaborations
(15)
Denise Roe
Mutual work: 3 Proposals
Collaboration Details
Baldassarre Stea
Mutual work: 2 Proposals
Collaboration Details
Megha Padi
Mutual work: 1 Proposal
Collaboration Details
Ritu Pandey
Mutual work: 4 Proposals﹒1 Grant
Collaboration Details
Wei Wang
Mutual work: 1 Proposal
Collaboration Details
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Courses
(1)
Cell Biology Basics
10+ Collaborators
$284.5K / $2.8M Funding
100+ Publications
