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Allyson Roof
Senior Lecturer
Physiology
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Research Area
pituitary,
signaling pathways,
homeostasis,
lactotrope,
prolactinoma,
erk/mapk activation,
lactotrope differentiation,
tumorigenic phenotype,
cell differentiation,
cancer biology
Publications
(8)
Recent
The balance of PI3K and ERK signaling is dysregulated in prolactinoma and modulated by dopamine
2018
signal transduction,
prolactinoma,
dopamine,
pi3k,
erk
Pituitary somatolactotropes evade an oncogenic response to Ras
2018
pituitary,
somatolactotropes,
oncogenic response,
ras,
evade
Consider the context: Ras/ERK and PI3K/AKT/mTOR signaling outcomes are pituitary cell type-specific
2018
signaling pathways,
cell type specificity,
pituitary cells,
ras/erk pathway,
pi3k/akt/mtor pathway
Mouse models for the analysis of gonadotropin secretion and action
2018
gonadotropin secretion,
mouse models,
hormonal regulation,
reproductive endocrinology,
endocrine system
Cell Cycle Progression Antagonizes ERK-Mediated PRL Promoter Activity Via PI3K/CDK4
2017
cell cycle progression,
erk signaling,
pi3k pathway,
cdk4,
prl promoter regulation
The Balance of Ras/ERK and PI3K/AKT/mTOR Signaling Regulates Pituitary Lactotrope Homeostasis and is Dysregulated in Prolactinoma
2017
pituitary,
lactotrope,
signaling,
prolactinoma,
homeostasis
Signaling pathways regulating pituitary lactotrope homeostasis and tumorigenesis.
2015
signaling pathways,
pituitary,
homeostasis,
tumorigenesis,
lactotrope
Persistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype.
2014
erk/mapk activation,
lactotrope differentiation,
tumorigenic phenotype,
cell differentiation,
cancer biology
Collaborations
(2)
Claudia Stanescu
Mutual work: 4 Publications
Collaboration Details
Hilary Lease
Mutual work: 3 Publications
Collaboration Details
Courses
(4)
Current Topics in Physiology
Fundamentals of Human Physiology
Human Anatomy and Physiology I
Physiology of Aging
7+ Publications