TRPV4 is a transient receptor potential ion channel that is widely expressed in various tissues and plays an important role in a range of physiological processes, including osmosensing, mechanotransduction, and thermosensation. It is implicated in various diseases and disorders, including chronic pain, osteoarthritis, and cardiovascular disease. Research in the field of TRPV4 focuses on understanding the molecular mechanisms underlying its function, as well as developing potential therapeutic strategies targeting this channel for the treatment of various conditions.