Treprostinil is a medication that belongs to the class of drugs called prostacyclin analogues. It is used in the treatment of pulmonary arterial hypertension (PAH) to help widen blood vessels and improve blood flow. Treprostinil works by mimicking the effects of prostacyclin, a naturally occurring substance in the body that helps to relax and dilate blood vessels. Research in the area of treprostinil focuses on its efficacy and safety in the treatment of PAH, as well as its potential use in other conditions such as scleroderma-related PAH or chronic thromboembolic pulmonary hypertension. Studies also explore the optimal dosing, administration methods, and long-term outcomes of treprostinil therapy. Additionally, research may investigate the underlying mechanisms of action of treprostinil and its potential benefits in combination with other PAH medications.