Subphenotypes refer to specific characteristics or features within a larger population or group that can help differentiate between individuals with a certain condition or disease. These subphenotypes may indicate different disease manifestations, responses to treatment, or prognosis. For example, in asthma research, subphenotypes may include variations in inflammatory markers, lung function, response to bronchodilators, or triggers for exacerbations. Identifying these subphenotypes can help researchers and clinicians better tailor treatments and interventions to individual patients, leading to more personalized and effective care. Overall, studying subphenotypes in research can provide valuable insights into the heterogeneity of diseases and conditions, potentially leading to more targeted and successful approaches to treatment and management.