Proteostasis is the term used to describe the process by which proteins are correctly folded, assembled, and regulated within cells to maintain a healthy cellular environment. This includes mechanisms such as protein folding, quality control, degradation, and turnover, as well as the regulation of protein synthesis and post-translational modifications. Disruptions in proteostasis can lead to the accumulation of misfolded or damaged proteins, which can contribute to various diseases such as neurodegenerative disorders, cancer, and metabolic disorders. Researchers study proteostasis to better understand how cells maintain protein homeostasis and to develop new therapeutic strategies for diseases associated with protein misfolding.