P-glycoprotein, also known as P-gp, is a protein that is found in the cell membranes of various tissues in the body, including the intestines, liver, and kidney. It plays a crucial role in transporting substances across these membranes, particularly in removing toxins and harmful compounds from cells. Research in the area of p-glycoprotein focuses on understanding its function and role in drug resistance, as it is known to actively pump drugs out of cells, reducing their effectiveness in treating diseases such as cancer. Scientists are also investigating ways to modulate or inhibit p-glycoprotein to improve drug delivery and overcome drug resistance in various medical conditions.