Naloxone is a medication used to counteract the effects of opioid overdose by blocking the receptors in the brain that opioids bind to. It is often administered in emergency situations, such as when a person is experiencing respiratory depression due to opioid overdose. Naloxone can quickly reverse the effects of opioids and save lives. Research in this area focuses on the effectiveness of naloxone in preventing opioid-related deaths, as well as improving access to and distribution of naloxone to those at risk of overdose. Additionally, research explores optimal dosing strategies, methods of administration, and potential barriers to naloxone use in various populations.