Motoneurons are nerve cells located in the spinal cord and brainstem that send signals to muscles to initiate movement. They serve as the final pathway through which the brain communicates with muscles to produce voluntary movements. Motoneurons play a crucial role in the control of movement and motor functions, as they receive inputs from various parts of the central nervous system and relay these signals to muscles to produce coordinated movements. Research in this area focuses on understanding the structure, function, and regulation of motoneurons, as well as their role in motor learning, development, and disease. Studying motoneurons can provide insights into the underlying mechanisms of movement disorders, such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy, and may lead to the development of new therapies for these conditions.