Mechanosensing is the process by which cells and organisms detect and respond to mechanical forces or stimuli in their environment. This can involve the sensing of physical forces such as compression, tension, or shear stress, and can occur at various levels of complexity, from individual cells to entire organisms. Mechanosensing is important for a wide range of biological processes, including cell migration, tissue development, and responses to physical cues in the environment. Researchers in this field study the mechanisms by which cells and organisms sense mechanical forces, as well as the downstream signaling pathways and biological responses that result from these mechanical stimuli. Understanding mechanosensing can have important implications for various fields, including tissue engineering, regenerative medicine, and the development of new therapeutics for diseases related to abnormal mechanosensitivity.